ID G3U643_LOXAF Unreviewed; 429 AA.
AC G3U643;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Small ArfGAP 1 {ECO:0000313|Ensembl:ENSLAFP00000023301.1};
GN Name=SMAP1 {ECO:0000313|Ensembl:ENSLAFP00000023301.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000023301.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000023301.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023301.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000023301.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023301.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3U643; -.
DR Ensembl; ENSLAFT00000026438.1; ENSLAFP00000023301.1; ENSLAFG00000007948.3.
DR GeneTree; ENSGT00940000155884; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd08839; ArfGap_SMAP; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR044732; ArfGAP_SMAP1-like.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF8; STROMAL MEMBRANE-ASSOCIATED PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 1..97
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 136..185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 396..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 429 AA; 46106 MW; 70CD1FDD0943CC90 CRC64;
GPRWASWNIG VFICIRCAGI HRNLGVHISR VKSVNLDQWT PEQIQCMQDM GNTKARLLYE
ANLPENFRRP QTDQAVEFFI RDKYEKKKYY DKNAIAITNI SSSDAPLQPL VSSPSLQAAV
EKNKLEVWKN NSEVPQKAMK WTEKPAKPLT TEKLQKKEDQ QLELKKSTSP KKTAEPTVDL
LGLDGPAEAP VTNGNTTTMP ALNDDLDIFG PMISNPLPTT VMPPAQGTLT VPAAAPLSIA
PGDLDLFTEQ TTKAEESTKK QLSKDSILSL YGTGTIQQQN TPGMFMGPAN IPFTSQAPPA
FQGFPSMGVP VPAAPGLMGN VMGQSASMMV GMPMPNGFMG SAQTGVMPLP QNVAGPQGGM
VGQMGASQSK FGLPQTQQPQ WSLSQMNQQM AGMSINSANP AVGFGQPPST TAGWSGSSSG
QTLSTQLWK
//
