ID   G3U7E7_LOXAF            Unreviewed;       317 AA.
AC   G3U7E7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   RecName: Full=long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00026121};
DE            EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000023755.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000023755.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023755.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000023755.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000023755.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC       {ECO:0000256|ARBA:ARBA00006432}.
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DR   AlphaFoldDB; G3U7E7; -.
DR   STRING; 9785.ENSLAFP00000023755; -.
DR   Ensembl; ENSLAFT00000029917.1; ENSLAFP00000023755.1; ENSLAFG00000032127.1.
DR   eggNOG; KOG1179; Eukaryota.
DR   GeneTree; ENSGT00940000159323; -.
DR   HOGENOM; CLU_000022_46_1_1; -.
DR   InParanoid; G3U7E7; -.
DR   OMA; YMNESAT; -.
DR   TreeFam; TF313430; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43107; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN; 1.
DR   PANTHER; PTHR43107:SF7; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN 1; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT   DOMAIN          194..269
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   317 AA;  35604 MW;  AD7FAF487EF8B315 CRC64;
     CTIVIQYIGE ICRYLLKQPV REAEKRHRVR LAIGNGLRPA IWEEFTQRFG VRQIGEFYGA
     TECNCSIANM DGKVGSCGFN SRILPNVYPI RLVKVNEETM ELQRDVQGLC IPCQAGEPGL
     LVGQINQQDP LRRFDGYMNE SATNKKIAHS VFHKGDSAYL SGDVLVMDEL GYMYFRDRSG
     DTFRWRGENV STTEVEGVLS RLLAQTDVAV YGVAVPGVEG KAGMAAIVDP HGQLSPNALY
     QELQKELAPY ARPIFLRLLP QMDTTGTFKI QKTRLQHEGF DPRQTSDRLF FLDLKQGHYL
     PLDEGIYGRI CSGAFSL
//