ID G3U8T0_LOXAF Unreviewed; 138 AA.
AC G3U8T0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial {ECO:0000256|ARBA:ARBA00015185};
DE AltName: Full=Complex I-20kD {ECO:0000256|ARBA:ARBA00030829};
DE AltName: Full=NADH-ubiquinone oxidoreductase 20 kDa subunit {ECO:0000256|ARBA:ARBA00032998};
GN Name=NDUFS7 {ECO:0000313|Ensembl:ENSLAFP00000024238.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000024238.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000024238.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000024238.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000024238.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000024238.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 20 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00009173, ECO:0000256|RuleBase:RU004464}.
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DR AlphaFoldDB; G3U8T0; -.
DR STRING; 9785.ENSLAFP00000024238; -.
DR Ensembl; ENSLAFT00000030319.1; ENSLAFP00000024238.1; ENSLAFG00000027030.1.
DR eggNOG; KOG1687; Eukaryota.
DR GeneTree; ENSGT00390000006565; -.
DR HOGENOM; CLU_055737_7_3_1; -.
DR InParanoid; G3U8T0; -.
DR OMA; IYDQMCE; -.
DR TreeFam; TF312859; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:Ensembl.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:Ensembl.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:Ensembl.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:Ensembl.
DR Gene3D; 3.40.50.12280; -; 1.
DR InterPro; IPR006137; NADH_UbQ_OxRdtase-like_20kDa.
DR InterPro; IPR006138; NADH_UQ_OxRdtase_20Kd_su.
DR NCBIfam; TIGR01957; nuoB_fam; 1.
DR PANTHER; PTHR11995; NADH DEHYDROGENASE; 1.
DR PANTHER; PTHR11995:SF14; NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL; 1.
DR Pfam; PF01058; Oxidored_q6; 1.
DR SUPFAM; SSF56770; HydA/Nqo6-like; 1.
DR PROSITE; PS01150; COMPLEX1_20K; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|RuleBase:RU004464};
KW Iron {ECO:0000256|RuleBase:RU004464};
KW Iron-sulfur {ECO:0000256|RuleBase:RU004464};
KW Metal-binding {ECO:0000256|RuleBase:RU004464};
KW NAD {ECO:0000256|RuleBase:RU004464};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 13..122
FT /note="NADH:ubiquinone oxidoreductase-like 20kDa subunit"
FT /evidence="ECO:0000259|Pfam:PF01058"
SQ SEQUENCE 138 AA; 15734 MW; D2BB9EC22C85124D CRC64;
QSSLWPMTFG LACCAVEMMH MAAPRYDMDR FGVVFRASPR QADVMIVAGT LTNKMAPALR
KVYDQMPEPR YVVSMESCAN GGGYYHYSYS VVRGCDRIVP VDIYVPGCPP TAEALLYGIL
QLQKKIKREK RLNIWYRR
//
