ID G3UBF5_LOXAF Unreviewed; 356 AA.
AC G3UBF5;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Protein phosphatase 1 regulatory subunit 42 {ECO:0000256|ARBA:ARBA00044175};
DE AltName: Full=Leucine-rich repeat-containing protein 67 {ECO:0000256|ARBA:ARBA00044209};
GN Name=PPP1R42 {ECO:0000313|Ensembl:ENSLAFP00000025163.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000025163.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000025163.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000025163.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000025163.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000025163.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}.
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DR RefSeq; XP_003408259.2; XM_003408211.2.
DR AlphaFoldDB; G3UBF5; -.
DR STRING; 9785.ENSLAFP00000025163; -.
DR Ensembl; ENSLAFT00000036105.1; ENSLAFP00000025163.1; ENSLAFG00000030620.1.
DR eggNOG; KOG2769; Eukaryota.
DR GeneTree; ENSGT00940000158260; -.
DR HOGENOM; CLU_062444_0_0_1; -.
DR InParanoid; G3UBF5; -.
DR OMA; NNCISCM; -.
DR TreeFam; TF329227; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0002177; C:manchette; IEA:Ensembl.
DR GO; GO:0003779; F:actin binding; IEA:Ensembl.
DR GO; GO:0070840; F:dynein complex binding; IEA:Ensembl.
DR GO; GO:0015631; F:tubulin binding; IEA:Ensembl.
DR CDD; cd21340; PPP1R42; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR46652; LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46652:SF8; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 42; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SMART; SM00365; LRR_SD22; 5.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 4.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT REGION 301..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 41215 MW; 7BF16C24D575589A CRC64;
MVRLTVDLIA KTSNFKPRKE ETISQYLKKI THINFSDKNI DAIEDLSLCK NLSVLYLYDN
RISQITNLNF ATNLTHLYLQ NNCISCLENL RSLKKLEKLY LGGNYIAVIE GLEGLEELRE
LHVESQRLPL GEKLLFDPRT LYSLAKSLSI LNISNNNIDD IRDLEMLENL NQLIAVDNRL
LHVKDLEFLL SKLMKLWKMD LNGNPVCLKP KYRDRLILVS KSLEFLDGRE IKKMERQFLM
NWKASKDAKK ISKKRNTKSE DASNSYISNF ETMHHIVPVY YPQVGKPKLV FFSEIQRSFP
NGNASPETSQ EDTKTKVTEE MGNLSLKESQ SLLTKSDVHE PHLLQKSIEN SFMENE
//
