ID   G3UEJ8_LOXAF            Unreviewed;       267 AA.
AC   G3UEJ8;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=PHD finger protein 23 {ECO:0000313|Ensembl:ENSLAFP00000026256.1};
GN   Name=PHF23 {ECO:0000313|Ensembl:ENSLAFP00000026256.1};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000026256.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000026256.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026256.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000026256.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026256.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the PHF23 family.
CC       {ECO:0000256|ARBA:ARBA00037988}.
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DR   AlphaFoldDB; G3UEJ8; -.
DR   Ensembl; ENSLAFT00000032207.1; ENSLAFP00000026256.1; ENSLAFG00000022349.2.
DR   GeneTree; ENSGT00530000063882; -.
DR   HOGENOM; CLU_047981_0_0_1; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   CDD; cd15631; PHD_PHF23; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR14571:SF8; PHD FINGER PROTEIN 23; 1.
DR   PANTHER; PTHR14571; UNCHARACTERIZED; 1.
DR   Pfam; PF13831; PHD_2; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
PE   3: Inferred from homology;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          215..259
FT                   /note="Zinc finger PHD-type"
FT                   /evidence="ECO:0000259|SMART:SM00249"
FT   REGION          35..195
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..107
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        146..166
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..190
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   267 AA;  29124 MW;  247D1253E86FBD2F CRC64;
     SLFSSFQPPE KRRRTIEDFN KFCSFVLAYA GYIPPSKEES DWPASGSSSP LRGESAADSD
     GWDSAPSDLR PGPPRSTFSR LQAPDSATLL EKMKLKDSLF DLDGPKKSKK RKLKKAERGD
     RLPPPGPPRA PPSDTDAAVV GAEAPAPVFP TPPEAPRPPA TGPPEGAPPT DSESKEVGST
     ETSQDGDASS SEGEMRVMDE DIMVESGDDS WDLITCYCRK PFAGRPMIEC SLCGTWIHLS
     CAKIKKTNVP DFFYCQKCKE LRPEARR
//