ID G3UES8_LOXAF Unreviewed; 1121 AA.
AC G3UES8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Cell adhesion associated, oncogene regulated {ECO:0000313|Ensembl:ENSLAFP00000026336.1};
GN Name=CDON {ECO:0000313|Ensembl:ENSLAFP00000026336.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000026336.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000026336.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026336.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000026336.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026336.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3UES8; -.
DR Ensembl; ENSLAFT00000034719.1; ENSLAFP00000026336.1; ENSLAFG00000008045.4.
DR GeneTree; ENSGT00940000157114; -.
DR HOGENOM; CLU_008503_0_0_1; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 8.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF30; FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13927; Ig_3; 3.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 5.
DR SMART; SM00408; IGc2; 5.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1121
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003456516"
FT TRANSMEM 966..991
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..114
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 124..204
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 225..303
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 310..396
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 405..516
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 579..677
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 725..820
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 828..928
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 533..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 682..701
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 938..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 941..959
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1121 AA; 121817 MW; F1D43BF189818637 CRC64;
MHPDPGSLQT LLWSTLMILG SSVSADLTPS FISEPLSAVQ KLGGPVVLHC SAKPVTAQIS
WLLNGKRLDR NTDQIKMRQG TLTIPSLNPS LSGSYQCIAN NSIGAIVSGP AVVSTAVLGD
FGSPTKNVIT AEEKSTAFIG CKVPDSNPKA EVRYKIRGKW LKHSTDNYLI LPSGNLQILN
VSSEDRGSYK CAVYNPVTQE LKVEPIGRKL LVSRPSSDDF HILHPTLSQA LAVLSYSPVT
LECVVRGVPA SQVYWLKDGQ DVVLGSNWRR LYSHLATDSI DPGDAGNYSC VVGNRSGDLK
HVTYMVNVLE RASISEGLQD QMVSLGATVH FTCDVHGNPV PNRTWFHNAR PIHPSPRHLT
TGNGLEISGV TMEDSGLYQC IADNGIGFVQ STGRLDIEKD SGFKPVIITA PASAKVVDGD
IVTLSCNATG LPVPVIRWYD SHGLITSHPS QILRSKSRKS HLVRPEAVNL EPVYFIMSRA
GSSSLYIQAV TQEHAGKYIC EATNDHGTVY SEAFITVVPF ETNTKAETVT LSDAAQSDDR
ETRNVSEAGS LSSLPVKSRS SAVESSSVKN ASSASVPDAP IILSPPQTHT PDTYNLVWRS
GKDGGLPINA YFVKYRKLDD AVGVVGSWHT VRVPGSENEL HLTELEPSSL YEVLMVARSA
AGEGQPAMLT FRTSKAFLEK TASSKNTQAS APPMGIPKHP VDSEVTNNFG VVLTDSSRHS
GVPEAPDRPT ISTASETSVY VTWIPRANGG SPITAFKVEY KRMRSSDWLV AAEDIPPSKL
SVEVRSLEPG STYKFRVIAI NHYGESFRSS ASRPYQVAGF SNRFSNRPIT GPHIAYTEAV
SDTEIMLKWT YIPSSNNNTP IQGFYIYYRP TDSDNDSDYK RDVVEGSKQW HMIGHLQPET
SYDIKMQCFN EGGESEFSNV MICETKVKRV PGASEYPVRD LSTPPNFSGS GGNVGPATSP
TRSSDMLYLI VGCVLGVMVL ILMVFIAMCL WRNRQQSTIQ KYDPPGYLYQ GSDVNGQVVE
YTTLPGTSRV NGHVHGSIMR NGSLSNGCSH LHHKVSNGVN AFVNGSLNGG LCSGHTNTLA
RTRVDFEHPH HLLNGAGMYK AVPQTDPLEC VNCRNCRNNN R
//
