ID   G3UEY1_LOXAF            Unreviewed;       441 AA.
AC   G3UEY1;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=ELKS/RAB6-interacting/CAST family member 2 {ECO:0008006|Google:ProtNLM};
OS   Loxodonta africana (African elephant).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX   NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000026389.1, ECO:0000313|Proteomes:UP000007646};
RN   [1] {ECO:0000313|Ensembl:ENSLAFP00000026389.1, ECO:0000313|Proteomes:UP000007646}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026389.1,
RC   ECO:0000313|Proteomes:UP000007646};
RA   Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT   "The Genome Sequence of Loxodonta africana (African elephant).";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSLAFP00000026389.1}
RP   IDENTIFICATION.
RC   STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000026389.1};
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; G3UEY1; -.
DR   STRING; 9785.ENSLAFP00000026389; -.
DR   Ensembl; ENSLAFT00000034071.1; ENSLAFP00000026389.1; ENSLAFG00000032538.1.
DR   eggNOG; KOG4809; Eukaryota.
DR   GeneTree; ENSGT00650000093320; -.
DR   HOGENOM; CLU_009304_1_0_1; -.
DR   InParanoid; G3UEY1; -.
DR   OMA; CITCQPL; -.
DR   TreeFam; TF324969; -.
DR   Proteomes; UP000007646; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0098793; C:presynapse; IEA:UniProt.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   InterPro; IPR019323; ELKS/CAST.
DR   PANTHER; PTHR18861; ELKS/RAB6-INTERACTING/CAST PROTEIN; 1.
DR   PANTHER; PTHR18861:SF3; ERC PROTEIN 2; 1.
DR   Pfam; PF10174; Cast; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT   REGION          397..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          23..334
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   441 AA;  51643 MW;  2193C47A8459F8F9 CRC64;
     QELHRRSQLQ PEPAKTKALQ TVIEMKDTKI ASLERNIRDL EDEIQMLKAN GVLNTEDREE
     EIKQIEVYKS HSKFMKTKID QLKQELSKKE SELLALQTKL ETLSNQNSDC KQHIEVLKES
     LTAKEQRAAI LQTEVDALRL RLEEKESFLN KKTKQLQDLT EEKGTLAGEI RDMKDMLEVK
     ERKINVLQKK IENLQEQLRD KDKQLMNLKD RVKSLQTDSS NTDTALATLE EALSEKERII
     ERLKEQRERD DRERLEEIES FRKENKDLKE KVNALQAELT EKESSLIDLK EHASSLASAG
     LKRDSKLKSL EIAIEQKKEE CSKLEAQLKK AHNIEDDSRM NPEFADRMKQ LDKEASYYRD
     ECGKAQAEVD RLLEILKEVE NEKNDKDKKI AELERHMKDQ NKKVANLKHN QQLEKKKNAQ
     LLEEVRRRED SMADNSQHLQ V
//