ID G3UHW4_LOXAF Unreviewed; 1836 AA.
AC G3UHW4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Obscurin like cytoskeletal adaptor 1 {ECO:0000313|Ensembl:ENSLAFP00000027422.1};
GN Name=OBSL1 {ECO:0000313|Ensembl:ENSLAFP00000027422.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000027422.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000027422.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000027422.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000027422.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000027422.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 9785.ENSLAFP00000027422; -.
DR Ensembl; ENSLAFT00000033350.1; ENSLAFP00000027422.1; ENSLAFG00000022947.2.
DR eggNOG; KOG0613; Eukaryota.
DR GeneTree; ENSGT00940000156702; -.
DR InParanoid; G3UHW4; -.
DR OMA; KAEVRWY; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:1990393; C:3M complex; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005794; C:Golgi apparatus; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0007030; P:Golgi organization; IEA:Ensembl.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IEA:Ensembl.
DR GO; GO:0050775; P:positive regulation of dendrite morphogenesis; IEA:Ensembl.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:Ensembl.
DR GO; GO:0007088; P:regulation of mitotic nuclear division; IEA:Ensembl.
DR CDD; cd00063; FN3; 1.
DR CDD; cd00096; Ig; 2.
DR CDD; cd20967; IgI_C2_MyBP-C-like; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 19.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR35971:SF6; OBSCURIN-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR35971; SI:DKEY-31G6.6; 1.
DR Pfam; PF07679; I-set; 12.
DR Pfam; PF13927; Ig_3; 1.
DR SMART; SM00409; IG; 17.
DR SMART; SM00408; IGc2; 13.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 17.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 13.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Immunoglobulin domain {ECO:0000256|ARBA:ARBA00023319};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 79..176
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 193..281
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 290..376
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 468..566
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 665..751
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 755..840
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 853..933
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 937..1026
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1029..1116
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1120..1212
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1216..1294
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1309..1394
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1577..1651
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1741..1822
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 53..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..195
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1836 AA; 199982 MW; AA64BB1D92487314 CRC64;
GLGVSAQKRS SGPRXGAEHG LLLSGALPDA GVYVCRARNS AGEAYAAAAV TVLEPPAPEP
EPQAAERPLP QPGAGEGAPV FLTGPGSQWV LRGAEVVLTC QVGGLPEPTL YWEKDGMALD
EVWDSSHFAL VPGRAEGGRG VSLALRILAA RLPDSGVYVC HARNPHGHAQ AGALLQVHQP
PESPPADPDE APPPVVEPLK CAPKTFWVNE GKHAKFRCYV MGKPEPEIEW HWEGRPLLPD
RRRLMYRDRD GGFVLKVLYC QAKDRGLYVC AARNSAGQTL SAVRLHVKEP RLRFTRPLQD
VEGREHGIVV LECKVPNSRI PTAWFREDQR LLPCRKYEQI EEGTVRRLII HRLKADDDGV
YLCEMRGRVR SVANVTVKGP ILKRLPRKLD VLEGENAVLL VETREAGSEG HWSRDGEDLP
ATCQSSSGHM HALVLPGVTR EDAGEVTFNV GNSRTTTLLR VKCVKHSPPG PPVLAEMFKG
HKNTVLLTWK PPEPAPETPF IYRLERQEVG SEDWVQCFSV EKAGAVEVPG DCVPVEGDYR
FRVCTVSEHG RSSHVVFQGS AHLVPTARLV AGLEDVQVYD GEDAVFSLDL STIIQGTWFL
NGQELKSDEP EGQVEPGALR YCVEQKGLQH RLILQSVKHQ DSGALVGFSC PGVQDSAALT
IQESPVHILS PQDRVSLTFT TSERVVLTCE LSRLDFPASW YKDGQEVMES ESLVVKVDGR
KHRLILPAAE VRDSGEFECR TEGVSAFFSV TVQDPPVHIL DPQEHVFVHA ITSECVMLTC
EVDREDAEVH WYKDGQEVEE GDFLVLENEG PHHRLVLPAA QPPDGGEFQC VAGEERAYFT
VTITDVSSWI VYPSGKVYVA AVRLERVVLT CELCRPWAEV RWTKDGEEVV ESPALLLQKE
DTVRRLVLPA VQLEDSGEYL CEIDDESASF TVTVTEPPVR IIYPRDEVTL IAVSLECVVL
LCELSRDDAP VRWYKDGLEV EESEALVLES DGPRRRLVLP AAQPGDGGEF VCDAGDDSAF
FTVTVTAPPE RIVHPAARAL DLQFRAPGRV ELRCEVAPAG SQVRWYRDGL EVEASDTLQL
GAEGPARTLT LPHAQPEDAG EYVCETRDEA VTFNVSLAEP PVQFLAPETA PSPLCVAPGE
LVVLSCELSR ASAPVLWSHN GRPVQEGEGL ELQAEGPRRV LCIRAATLAH AGLYTCQCRA
APGAPSLSFT VQVAGPPFRV VAPEAAQTRV RSTPGGDLEL VVHLSGPGGP VRWYKDGERL
ASHGRVQLEQ AGARQVLRVQ EARTGDAGEY LCDAPQDSRI FLVSVEEPPP MKLVSELTPL
TVHEGDDATF RCEVSPPDTD VTWLRNGAIV TPGPQLEITQ NGLSHTLTMR GCQLQDAGTV
TARAGGMATS ARLHVREAEL LFLRRLQDVR VEEGQDVCLE VETGRVGAAG AVRWVRGREP
LPHDARLSMA QDGHIHRLFI HGVVLADQGT YGCESHHDRT LARLSVRPKQ LRALQPLEDV
TISEGGSATF LELSQEGVAG EWARGGVVEP GPKCHIHAEG HSHRLVLSGL GRADSGCVSF
TADSLRCAAR LTVREAPVTI MWGPQDLEVT EGDTATFECK LSQALADVTW EKDGRALAPS
PRLRLQALGA RRLLQLRCCG PSDAGTYSCA VGTVRGGYGR CGSRALRGRG AAVETCPGAD
PAFTGEGRTL PGGIAQSRLS WRWKGTGRWH KPAAGSGGRR EGRYASPPGC PACPINLSPR
PPTLALPLQM CRRPPREKTV LVGRRAVLEV TVSRLGGHVC WLREGVELCP GDKYELRSHG
PTHSLVIHDV RPEDQGTYCC QAGQDSAHTR LLVEGE
//
