ID G3UJJ7_LOXAF Unreviewed; 421 AA.
AC G3UJJ7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Ankyrin repeat and SOCS box containing 6 {ECO:0000313|Ensembl:ENSLAFP00000028006.1};
GN Name=ASB6 {ECO:0000313|Ensembl:ENSLAFP00000028006.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000028006.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000028006.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028006.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000028006.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028006.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR AlphaFoldDB; G3UJJ7; -.
DR STRING; 9785.ENSLAFP00000028006; -.
DR Ensembl; ENSLAFT00000035683.1; ENSLAFP00000028006.1; ENSLAFG00000002346.2.
DR eggNOG; KOG0504; Eukaryota.
DR GeneTree; ENSGT00390000006784; -.
DR OMA; HLCRVHI; -.
DR TreeFam; TF330837; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd03725; SOCS_ASB6; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.750.20; SOCS box; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR037327; ASB6_SOCS.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR036036; SOCS_box-like_dom_sf.
DR PANTHER; PTHR24132; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR PANTHER; PTHR24132:SF24; ANKYRIN REPEAT AND SOCS BOX PROTEIN 6; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF07525; SOCS_box; 1.
DR SMART; SM00248; ANK; 5.
DR SMART; SM00969; SOCS_box; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF158235; SOCS box-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS50225; SOCS; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT REPEAT 102..134
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 136..169
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 360..415
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 421 AA; 47004 MW; 572985A783CEB374 CRC64;
MPFLHGFRRI IFEYQPLVDA ILGSLGIQDP EPQEPLDGPN SSSIEESRIL VLTELLERKA
HSPFYQEGVS NALLKMAELG LTRAADVLLR NGANLNFEDP VTYYTALHIA VLRNQPNMVE
LLVRHGADIN RRDRIHESSP LDLASEEPER LPCLQRLLDL GADVNAADKH GKTALLHALA
SSDGVQIHNT ENIRLLLEGG ADVKATTKDG DTVFTCIIFL LGETVGGDKE EAQLINRFCF
QVTQLLLAHG ADPSECPAHE SLTHICLKSF KLHFPLLRFL LESGAAYNCS LHGASCWSGF
HIIFERLCSH PGCAEDESHV DLLRKAETVL DLMVTNSQKL QLPENFDIHP VGSLAGKIQA
LHFSLRQLEN YPPPLKHLCR VYIRLYLQPW PVDVKVKALP LPDRLKWYLL SEHSGTLQDD
I
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