ID G3ULK7_LOXAF Unreviewed; 387 AA.
AC G3ULK7;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Sprouty related EVH1 domain containing 3 {ECO:0000313|Ensembl:ENSLAFP00000028716.1};
GN Name=SPRED3 {ECO:0000313|Ensembl:ENSLAFP00000028716.1};
OS Loxodonta africana (African elephant).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta.
OX NCBI_TaxID=9785 {ECO:0000313|Ensembl:ENSLAFP00000028716.1, ECO:0000313|Proteomes:UP000007646};
RN [1] {ECO:0000313|Ensembl:ENSLAFP00000028716.1, ECO:0000313|Proteomes:UP000007646}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028716.1,
RC ECO:0000313|Proteomes:UP000007646};
RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., Lindblad-Toh K.;
RT "The Genome Sequence of Loxodonta africana (African elephant).";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSLAFP00000028716.1}
RP IDENTIFICATION.
RC STRAIN=Isolate ISIS603380 {ECO:0000313|Ensembl:ENSLAFP00000028716.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3ULK7; -.
DR Ensembl; ENSLAFT00000035219.1; ENSLAFP00000028716.1; ENSLAFG00000028517.1.
DR GeneTree; ENSGT00940000161445; -.
DR Proteomes; UP000007646; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0009966; P:regulation of signal transduction; IEA:InterPro.
DR CDD; cd10574; EVH1_SPRED-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041937; SPRE_EVH1.
DR InterPro; IPR007875; Sprouty.
DR InterPro; IPR000697; WH1/EVH1_dom.
DR PANTHER; PTHR11202:SF19; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR11202; SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER; 1.
DR Pfam; PF05210; Sprouty; 1.
DR Pfam; PF00568; WH1; 1.
DR SMART; SM00461; WH1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS51227; SPR; 1.
DR PROSITE; PS50229; WH1; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007646}.
FT DOMAIN 1..113
FT /note="WH1"
FT /evidence="ECO:0000259|PROSITE:PS50229"
FT REGION 119..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 41412 MW; 35EC4E0DE02FA6ED CRC64;
WCGVRAVVMT RDDSSGGWLP VGGGGLSQVS VCRVRGARPE GGARQGHYVV HGERLRDQKT
TLECALRPGL VYNKVNPIFH HWSLGDCKFG LTFQSPAEAD EFQKSLLAAL GQAGEGDLLS
ASLPAPGSLT QDTAETPCPL TSHVDSDSSS SHSHQETPPA TVAAPIVTVE SASGFGPTTP
PQRRRSSAQV SPVLLEILGS SDSGFQSDLW DSSEYIKGML VLMEGGPSDC LIHHRVRAGI
WYPKDLGVWI PPPLRKELAV GLDSWTPGRR AGWGLRSLSL GPRRIGAARC VHCRALFRRR
ADGRGGRCAE APDPGRLLVR RLSCLWCAES LLYHCLSDAE GDFSDPCACV SLAVPCLCCY
APLRACHWVA ARCGCAGCGG RHEEAAR
//
