ID G3UP11_MELGA Unreviewed; 553 AA.
AC G3UP11;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Angel homolog 2 {ECO:0000313|Ensembl:ENSMGAP00000017297.1};
GN Name=ANGEL2 {ECO:0000313|Ensembl:ENSMGAP00000017297.1};
OS Meleagris gallopavo (Wild turkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Meleagridinae; Meleagris.
OX NCBI_TaxID=9103 {ECO:0000313|Ensembl:ENSMGAP00000017297.1, ECO:0000313|Proteomes:UP000001645};
RN [1] {ECO:0000313|Ensembl:ENSMGAP00000017297.1, ECO:0000313|Proteomes:UP000001645}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=20838655; DOI=10.1371/journal.pbio.1000475;
RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A.,
RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K.,
RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C.,
RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A.,
RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., de Jong P.,
RA Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., Lee M.K., Lee T.,
RA Mane S., Marcais G., Marz M., McElroy A.P., Modise T., Nefedov M.,
RA Notredame C., Paton I.R., Payne W.S., Pertea G., Prickett D., Puiu D.,
RA Qioa D., Raineri E., Ruffier M., Salzberg S.L., Schatz M.C., Scheuring C.,
RA Schmidt C.J., Schroeder S., Searle S.M., Smith E.J., Smith J.,
RA Sonstegard T.S., Stadler P.F., Tafer H., Tu Z.J., Van Tassell C.P.,
RA Vilella A.J., Williams K.P., Yorke J.A., Zhang L., Zhang H.B., Zhang X.,
RA Zhang Y., Reed K.M.;
RT "Multi-platform next-generation sequencing of the domestic turkey
RT (Meleagris gallopavo): genome assembly and analysis.";
RL PLoS Biol. 8:E1000475-E1000475(2010).
RN [2] {ECO:0000313|Ensembl:ENSMGAP00000017297.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_010705014.1; XM_010706712.2.
DR AlphaFoldDB; G3UP11; -.
DR Ensembl; ENSMGAT00000019107.2; ENSMGAP00000017297.1; ENSMGAG00000009662.3.
DR GeneTree; ENSGT00940000157391; -.
DR HOGENOM; CLU_016428_0_2_1; -.
DR OMA; WRPPQFC; -.
DR OrthoDB; 89725at2759; -.
DR TreeFam; TF316126; -.
DR Proteomes; UP000001645; Chromosome 2.
DR Bgee; ENSMGAG00000009662; Expressed in breast and 17 other cell types or tissues.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR045816; ANGEL2_N.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR PANTHER; PTHR12121; CARBON CATABOLITE REPRESSOR PROTEIN 4; 1.
DR PANTHER; PTHR12121:SF27; PROTEIN ANGEL HOMOLOG 2; 1.
DR Pfam; PF19339; ANGEL2_N; 1.
DR Pfam; PF03372; Exo_endo_phos; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001645}.
FT DOMAIN 1..166
FT /note="Protein angel homolog 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19339"
FT DOMAIN 177..493
FT /note="Endonuclease/exonuclease/phosphatase"
FT /evidence="ECO:0000259|Pfam:PF03372"
FT REGION 87..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 553 AA; 63228 MW; 18DD20E9DC4EF545 CRC64;
MLPRHVQRLG RDWIAHVNGS QVFAFGSPVP TCMRWAGHCP WASFPLPVPV DFSANWRLPP
FFGPWRQFQN SNWQLDNFAQ NSCFHLPNPS MKSEGEEPLT KKRRLSAQPD SPAFSEQKEA
LCVSVSQDEK SESNKKGNIK RHWEYFCQHS RTMKILESAE TDQSNREREA KFDFTVMSYN
ILSQNLLEDN SHLYKHCRQR LLIWTYRFPN ILQEIKQLDA DVLCLQEVQE DHYRKEIKSS
LESLGYHCEY KMRTGSKPDG CAICFKTSKF RLISSNPVEF FRRDIPLLDR DNVGLVLLLQ
PKFPCKTNAA ICIANTHLLY NPRRGDIKLT QLAMLLAEIA SVAPQKNGIF CPIIICGDFN
SVPGSPLYRF IKEGKLNYEG LAIGKVSGQE QFPRGQRILS IPIWPKKLGI SQNCVYEIKQ
QQKEEDAGEK TEEATSDNTK EIVIASEKLS SKLQHRFKLS SVYSHYFPEN GLPEVTTCHS
RSAVTVDYIF YSAANDDSVA QPGTEDSLHG GLKLLRRLAL LTEKDLWTVN GLPNENNSSD
HLPLLAEFRL IER
//
