ID G3UZ08_MOUSE Unreviewed; 323 AA.
AC G3UZ08;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10 {ECO:0000313|Ensembl:ENSMUSP00000134298.2};
GN Name=Adamts10 {ECO:0000313|Ensembl:ENSMUSP00000134298.2,
GN ECO:0000313|MGI:MGI:2449112};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000134298.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000134298.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134298.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000134298.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000134298.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Antibodypedia; 51079; 193 antibodies from 29 providers.
DR Ensembl; ENSMUST00000173013.8; ENSMUSP00000134181.2; ENSMUSG00000024299.18.
DR Ensembl; ENSMUST00000173030.8; ENSMUSP00000134549.2; ENSMUSG00000024299.18.
DR Ensembl; ENSMUST00000173241.8; ENSMUSP00000134298.2; ENSMUSG00000024299.18.
DR Ensembl; ENSMUST00000173931.8; ENSMUSP00000133434.2; ENSMUSG00000024299.18.
DR UCSC; uc008byo.2; mouse.
DR AGR; MGI:2449112; -.
DR MGI; MGI:2449112; Adamts10.
DR VEuPathDB; HostDB:ENSMUSG00000024299; -.
DR GeneTree; ENSGT00940000158404; -.
DR HOGENOM; CLU_064871_0_0_1; -.
DR ChiTaRS; Adamts10; mouse.
DR Proteomes; UP000000589; Chromosome 17.
DR Bgee; ENSMUSG00000024299; Expressed in humerus cartilage element and 198 other cell types or tissues.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR002870; Peptidase_M12B_N.
DR PANTHER; PTHR11905; ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN; 1.
DR PANTHER; PTHR11905:SF159; MIND-MELD, ISOFORM J; 1.
DR Pfam; PF01562; Pep_M12B_propep; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..323
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015091583"
FT DOMAIN 40..129
FT /note="Peptidase M12B propeptide"
FT /evidence="ECO:0000259|Pfam:PF01562"
FT REGION 293..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 323 AA; 35981 MW; 401C6B18EE2A9A98 CRC64;
MASACQILRW ALALGLGLTF KVTHAFRSQD ELLSSLESYE IAFPTRVDHN GAMLAFSPPA
FRRQRRGAGA TTESRLFYKV AAPSTHFLLN LTRSPRLLAG HVSVEYWTRE GLAWQRAARA
HCLYAGHLQG QAGSSHVAVS TCGGLHGLIV ADDEEYLIEP LQGGPKGHRG PEESGPHVVY
KRSSLRHPHL DTACGVRDEK PWKGRPWWLR TLKPPPARPL GNESERGQLG LKRSVSRERY
VETLVVADKM MVAYHGRRDV EQYVLAIMNI VRLPNFSRTR VWETSSTSWS LASSCSQRTS
PPWRSPTMPG SHWTASVSGR NPS
//
