ID G3VDX6_SARHA Unreviewed; 294 AA.
AC G3VDX6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Protein prune homolog 2 {ECO:0000256|ARBA:ARBA00039860};
DE AltName: Full=BNIP2 motif-containing molecule at the C-terminal region 1 {ECO:0000256|ARBA:ARBA00042084};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000001380.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000001380.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000001380.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3VDX6; -.
DR STRING; 9305.ENSSHAP00000001380; -.
DR Ensembl; ENSSHAT00000001396.2; ENSSHAP00000001380.2; ENSSHAG00000001230.2.
DR eggNOG; KOG4129; Eukaryota.
DR GeneTree; ENSGT00940000154422; -.
DR InParanoid; G3VDX6; -.
DR TreeFam; TF323914; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR InterPro; IPR022181; Bcl2-/adenovirus-E1B.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR PANTHER; PTHR12112; BNIP - RELATED; 1.
DR PANTHER; PTHR12112:SF11; PROTEIN PRUNE HOMOLOG 2; 1.
DR Pfam; PF12496; BNIP2; 1.
DR Pfam; PF13716; CRAL_TRIO_2; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 130..291
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT REGION 1..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..78
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 294 AA; 33659 MW; 85DC07010D5511C7 CRC64;
MDIPFEEGEL SPNSADMRPE PPNSLDLDGS HPRRIKLTAP NINLSLDQSE GSVLSDDNLD
SPDEIDINVD DLDTPDEADS FEYTVHEDPT SLQDSGQEAE SIPEYTAEEE REDNRLWRTV
VIGEQEQRID MKVIEPYKRV ISHGGYYGDG LNAIIVFAAC FLPDSSRADY HYVMENLFLY
VISTLELMVA EDYMIVYLNG ATPRRKMPGL GWMKKCYQMI DRRLRKNLKS FIIVHPSWFI
RTILAVTRPF ISSKFSSKIQ YVSTLSELSE LIPMECVHIP ESIINIDMKL KEKL
//
