ID G3VP58_SARHA Unreviewed; 275 AA.
AC G3VP58;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Transmembrane protein 45A {ECO:0000313|Ensembl:ENSSHAP00000004963.1};
GN Name=TMEM45A {ECO:0000313|Ensembl:ENSSHAP00000004963.1};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000004963.1, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000004963.1, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000004963.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM45 family.
CC {ECO:0000256|ARBA:ARBA00006948}.
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DR RefSeq; XP_003763592.1; XM_003763544.2.
DR RefSeq; XP_012399940.1; XM_012544486.1.
DR AlphaFoldDB; G3VP58; -.
DR Ensembl; ENSSHAT00000005012.2; ENSSHAP00000004963.1; ENSSHAG00000004347.2.
DR GeneID; 100919668; -.
DR KEGG; shr:100919668; -.
DR CTD; 55076; -.
DR eggNOG; ENOG502QU0J; Eukaryota.
DR GeneTree; ENSGT00940000155530; -.
DR HOGENOM; CLU_059568_0_1_1; -.
DR InParanoid; G3VP58; -.
DR OMA; CWHYALA; -.
DR OrthoDB; 1275684at2759; -.
DR TreeFam; TF328673; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR006904; DUF716.
DR InterPro; IPR042127; TMEM45.
DR PANTHER; PTHR16007; EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED; 1.
DR PANTHER; PTHR16007:SF21; TRANSMEMBRANE PROTEIN 45A; 1.
DR Pfam; PF04819; DUF716; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 218..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 275 AA; 32464 MW; 4C9D5878FC6DDDC9 CRC64;
MGSFRGHALP GSFFLFFGFW WSVKYIMKYV CKKHKRTCFL GSRAGFQRLE IIEGLIKVSM
SLIGMTAEQF VPDGPHLNLY NYEEKHWDHL MSWQHSTMYF FFGLSGLVDI LCFTIHALPV
SLSKMMLSNA FFVEGFIFYF HTHGRAMLDI YIHQLLFLSI IGAAIFIFME FFFRSNIVLE
LLRSSFVLLQ GSWFWQIAFV LYPPNGGPEW NEADHGNMLF LTMCFCWHYA FTFFILSMNY
AFITWLIRSK IKKTFPSDMR LLKNVERDQE SEEEI
//
