ID   G3VPL3_SARHA            Unreviewed;       461 AA.
AC   G3VPL3;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Keratin 36 {ECO:0000313|Ensembl:ENSSHAP00000005118.1};
GN   Name=KRT36 {ECO:0000313|Ensembl:ENSSHAP00000005118.1};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000005118.1, ECO:0000313|Proteomes:UP000007648};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000005118.1, ECO:0000313|Proteomes:UP000007648}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA   Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA   Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA   Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA   Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA   Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered marsupial
RT   Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000005118.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000256|RuleBase:RU000685}.
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DR   RefSeq; XP_003768276.1; XM_003768228.2.
DR   AlphaFoldDB; G3VPL3; -.
DR   STRING; 9305.ENSSHAP00000005118; -.
DR   Ensembl; ENSSHAT00000005168.2; ENSSHAP00000005118.1; ENSSHAG00000004477.2.
DR   GeneID; 100927688; -.
DR   KEGG; shr:100927688; -.
DR   CTD; 8689; -.
DR   eggNOG; ENOG502QQY9; Eukaryota.
DR   GeneTree; ENSGT00940000161311; -.
DR   HOGENOM; CLU_012560_8_0_1; -.
DR   InParanoid; G3VPL3; -.
DR   OMA; NDMRCQY; -.
DR   OrthoDB; 4640531at2759; -.
DR   TreeFam; TF332742; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0045095; C:keratin filament; IEA:Ensembl.
DR   GO; GO:0030280; F:structural constituent of skin epidermis; IEA:Ensembl.
DR   GO; GO:0045616; P:regulation of keratinocyte differentiation; IEA:Ensembl.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 1.20.5.500; Single helix bin; 1.
DR   Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   InterPro; IPR002957; Keratin_I.
DR   PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR   PANTHER; PTHR23239:SF204; KERATIN, TYPE I CUTICULAR HA6; 1.
DR   Pfam; PF00038; Filament; 1.
DR   PRINTS; PR01248; TYPE1KERATIN.
DR   SMART; SM01391; Filament; 1.
DR   SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW   ECO:0000256|RuleBase:RU000685};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT   DOMAIN          93..404
FT                   /note="IF rod"
FT                   /evidence="ECO:0000259|PROSITE:PS51842"
FT   COILED          90..131
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          203..241
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          302..329
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          355..389
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   461 AA;  52163 MW;  31FCAB955EC4A704 CRC64;
     MTSQICVPTF STGSFRGVCG TSSGLSRVSS IRSLGSCRVP NLSCSSGSIS SLKVGSCGSG
     SYLPNTYLSN GHHTSGFGGN SIWLGEGVFN GNEKETMQFL NDRLANYLEK VHQLQRENSA
     LEKKIREWYE SQIPYTCPDY QSYFKTIEDL QQKVLLTKAE NARLVLQIDN AKLAADDFRT
     KYETELSLRQ LIEADINGLR KILDELTLFK ADLEMQLESL KEELLCLKKS HEEEVSLLRS
     QLGDRLNVEV DAAPPVDLNK ILNDMRCQYE ALVENNRRDV ENWFTTQTEE LNQQVVSSSE
     QLQCCQSEII ELKRNVNALE IELQTQHSMR NSLESTLAET EARYGSQLTQ IQCMISSVEV
     QLAEIRCDLE RQNQEYQVLL DVKTRLESEI ATYRRLLEGE DCKLPVHPCA TEHKPVIRIP
     CPPSVPCNSG SQISTQIRTI TEEIKDGRII SSREHVQQRP L
//