ID G3VSU4_SARHA Unreviewed; 446 AA.
AC G3VSU4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Ankyrin repeat and MYND domain containing 2 {ECO:0000313|Ensembl:ENSSHAP00000006249.1};
GN Name=ANKMY2 {ECO:0000313|Ensembl:ENSSHAP00000006249.1};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000006249.1, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000006249.1, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000006249.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000256|ARBA:ARBA00004138}.
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DR RefSeq; XP_012407078.1; XM_012551624.1.
DR AlphaFoldDB; G3VSU4; -.
DR STRING; 9305.ENSSHAP00000006249; -.
DR Ensembl; ENSSHAT00000006303.2; ENSSHAP00000006249.1; ENSSHAG00000005439.2.
DR GeneID; 100917880; -.
DR KEGG; shr:100917880; -.
DR CTD; 57037; -.
DR eggNOG; KOG1710; Eukaryota.
DR GeneTree; ENSGT00390000016820; -.
DR HOGENOM; CLU_048951_0_0_1; -.
DR InParanoid; G3VSU4; -.
DR OMA; NNYVTRS; -.
DR OrthoDB; 2882203at2759; -.
DR TreeFam; TF351374; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 6.10.140.2220; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR24150; ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR24150:SF8; ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 2.
DR PROSITE; PS50088; ANK_REPEAT; 2.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT REPEAT 45..77
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 79..111
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 320..357
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT REGION 373..446
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..393
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 446 AA; 49859 MW; 99D2074749D5ACB8 CRC64;
MAPPKKGELT QEEKELLEVI GQGNVQEAGR LLGSKNVRVN CLDEHGMTPL MHAAYKGKID
MCRMLLRHGA NVNCNEHEHG YTALMFAGLS GNKEITRVML EAGADTDVVN SVGRTAAQMA
AFVGQHDCVT VINNFCPRER LDYYTKPQGL EKEPRLPPKL AGPLHKMVTT TNLHPVKIVM
LIKENPLLAE VDALKKCARV MELICEKCMK QRDMNEVLAM KMHYLSCVFQ KCAKFLSERE
DKLDGFIKSL LKGRESDGFP VYQEKFIREC IRKFPYCETT LLQQLVRSIA PVEIGSDPTA
FSVLTQAITG QVGFVDVEFC TTCGEKGADK RCSVCKMVIY CNQNCQKIHW FTHKKVCKEL
KAAYEKQELE AAKEKKRQEE RQKTEKEPEV DSNSNEEQPE PDPGVTGDES ADVAQEEKAE
ALPAASEADG AAGLQDMAGR VREPEE
//
