ID G3W086_SARHA Unreviewed; 473 AA.
AC G3W086;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Islet cell autoantigen 1 like {ECO:0000313|Ensembl:ENSSHAP00000008841.2};
GN Name=ICA1L {ECO:0000313|Ensembl:ENSSHAP00000008841.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000008841.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000008841.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000008841.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3W086; -.
DR STRING; 9305.ENSSHAP00000008841; -.
DR Ensembl; ENSSHAT00000008914.2; ENSSHAP00000008841.2; ENSSHAG00000007656.2.
DR eggNOG; KOG3891; Eukaryota.
DR GeneTree; ENSGT00390000005530; -.
DR HOGENOM; CLU_037158_1_0_1; -.
DR TreeFam; TF317186; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0019904; F:protein domain specific binding; IEA:InterPro.
DR CDD; cd07661; BAR_ICA69; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR010504; AH_dom.
DR InterPro; IPR024114; Islet_autoAg_Ica1/Ica1-like.
DR InterPro; IPR006723; Islet_autoAg_Ica1_C.
DR PANTHER; PTHR10164; ISLET CELL AUTOANTIGEN 1; 1.
DR PANTHER; PTHR10164:SF5; ISLET CELL AUTOANTIGEN 1-LIKE PROTEIN; 1.
DR Pfam; PF06456; Arfaptin; 1.
DR Pfam; PF04629; ICA69; 1.
DR SMART; SM01015; Arfaptin; 1.
DR SMART; SM01237; ICA69; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS50870; AH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 44..247
FT /note="AH"
FT /evidence="ECO:0000259|PROSITE:PS50870"
FT REGION 415..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 53021 MW; 504E078B53B4695F CRC64;
MDSFGTTKSE DDQSVVSRMQ KKYWKTKQVL IKATGKKEDE HVVASDAELD AKLEVFHSIQ
ETCTELLKII EKYQQRLNAI SEEENELGLF LKFQAEQDIT QAGKMMDATG KTLCSSANQR
LALCMPLSRL EQEVATFSQR AVSDTLMTIN RMEQARTEYR GALLWMKDVS QELDPDTSKQ
MEKFRKVQIQ VRTAKASFDK LKMDVCQKVD LLGASRCNLL SHSLTTYQRT LLGFWEKTAR
MMSRIHEEFT GFRPYDFVAL KRLKESPNNL TEEHKEDRVE NNILTANLDK LILLDEEASE
KESETASEDH KEDHFQMSEF EASQLSGPEN VAKDLLVDSL EGEDFEKEFS FLNNLLSPSS
SSTGEFNQEC QNVCGSPNTS VPAQNCAAGA ESLAKSSGFL PSQLFDLGLH AAGNFSNSDN
QPVPSQSKPK KSSISPEGGN NQDMSAWFNL FADLDPLSNP DAIGHSDDEL LNA
//
