ID G3W0H4_SARHA Unreviewed; 443 AA.
AC G3W0H4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=PTPRF interacting protein alpha 2 {ECO:0000313|Ensembl:ENSSHAP00000008929.2};
GN Name=PPFIA2 {ECO:0000313|Ensembl:ENSSHAP00000008929.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000008929.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000008929.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000008929.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the liprin family. Liprin-alpha subfamily.
CC {ECO:0000256|ARBA:ARBA00007026}.
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DR RefSeq; XP_012405945.1; XM_012550491.1.
DR AlphaFoldDB; G3W0H4; -.
DR STRING; 9305.ENSSHAP00000008929; -.
DR Ensembl; ENSSHAT00000009003.2; ENSSHAP00000008929.2; ENSSHAG00000007734.2.
DR eggNOG; KOG0249; Eukaryota.
DR GeneTree; ENSGT01050000244900; -.
DR HOGENOM; CLU_006923_2_0_1; -.
DR TreeFam; TF314207; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR CDD; cd09562; SAM_liprin-alpha1_2_3_4_repeat1; 1.
DR CDD; cd09565; SAM_liprin-alpha1_2_3_4_repeat2; 1.
DR CDD; cd09568; SAM_liprin-alpha1_2_3_4_repeat3; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 3.
DR InterPro; IPR029515; Liprin.
DR InterPro; IPR037620; Liprin-alpha_SAM_rpt_1.
DR InterPro; IPR037621; Liprin-alpha_SAM_rpt_2.
DR InterPro; IPR037622; Liprin-alpha_SAM_rpt_3.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12587; LAR INTERACTING PROTEIN LIP -RELATED PROTEIN; 1.
DR PANTHER; PTHR12587:SF6; LIPRIN-ALPHA-2; 1.
DR Pfam; PF00536; SAM_1; 2.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 3.
DR SUPFAM; SSF47769; SAM/Pointed domain; 3.
DR PROSITE; PS50105; SAM_DOMAIN; 3.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 115..181
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 213..270
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 294..363
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
SQ SEQUENCE 443 AA; 50140 MW; 1E64679B3FE90B1D CRC64;
MTHTLPSSYH NEARSSLAVS LESDSIGLGS ANSSQDSLHK APKKKGIKSS IGRLFGKKEK
ARLGQLRGFM ETEAAAQESL GLGKLGTQAE KDRRLKKKHE LLEEARRKGL PFAQWDGPTV
VAWLELWLGM PAWYVAACRA NVKSGAIMSA LSDTEIQREI GISNPLHRLK LRLAIQEMVS
LTSPSAPPTS RTCPVFLQTL AYGDMNHEWI GNEWLPSLGL PQYRSYFMEC LVDARMLDHL
TKKDLRVHLK MVDSFHRTSL QYGIMCLKRL NYDRKELERR REASQHEIKD VLVWSNDRVI
RWIQAIGLRE YANNVLESGV HGSLIALDEN FDYSSLALLL QIPTQNTQAR QILEREYNNL
LALGTERRLD ESDDKNFRRG SSWRRQFPPR EVHGISMMPG SSETLPAGFR LTTTSGQSRK
MATDVASSRL QRLDSSTVRT YSC
//
