ID G3W7R8_SARHA Unreviewed; 377 AA.
AC G3W7R8;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Cysteine and histidine-rich domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034547};
DE AltName: Full=CHORD domain-containing protein 1 {ECO:0000256|ARBA:ARBA00034558};
GN Name=CHORDC1 {ECO:0000313|Ensembl:ENSSHAP00000011473.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000011473.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000011473.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000011473.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3W7R8; -.
DR STRING; 9305.ENSSHAP00000011473; -.
DR Ensembl; ENSSHAT00000011569.2; ENSSHAP00000011473.2; ENSSHAG00000009863.2.
DR eggNOG; KOG1667; Eukaryota.
DR GeneTree; ENSGT00940000154174; -.
DR HOGENOM; CLU_040079_0_0_1; -.
DR InParanoid; G3W7R8; -.
DR TreeFam; TF105394; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:Ensembl.
DR GO; GO:0005524; F:ATP binding; IEA:Ensembl.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:Ensembl.
DR GO; GO:0008270; F:zinc ion binding; IEA:Ensembl.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IEA:Ensembl.
DR GO; GO:1900034; P:regulation of cellular response to heat; IEA:Ensembl.
DR GO; GO:0010824; P:regulation of centrosome duplication; IEA:Ensembl.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 4.10.1130.20; -; 2.
DR InterPro; IPR007051; CHORD_dom.
DR InterPro; IPR039790; CHRD1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR PANTHER; PTHR12621:SF7; CHORD DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR12621; CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN; 1.
DR Pfam; PF04968; CHORD; 2.
DR Pfam; PF04969; CS; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51401; CHORD; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 233..292
FT /note="CHORD"
FT /evidence="ECO:0000259|PROSITE:PS51401"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..33
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 44..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 377 AA; 42274 MW; 72796D11C969135D CRC64;
RSPYPQRPLW LLSPQPQTQS APPRRPPSPS APPGLSCACA RPESSRRFPK RNRPFPETDS
LKKSDSRLRL RSPCSRRCGP ASVSLLVAAE RKCPCCATTE AAASALILKP TRRGWSCCKR
RTTDFSDFLS IVGCTKGKHN DEKPPEPVKP EVKTTSEKKE LSELKPKFQE HIIQAPKPVE
AIKRPSPDEP MTNLELKIAA SLKQALDKLK LSSENEVDKK DEDSDEIKIG TSCKNGGCVK
TYQGPQSIEE VCIFHSGVPI FHEGMKYWSC CRRKTSDFNT FLAQEGCTTG KHLWTKKDAG
KKVVPCRHDW HQTGGQVTIS VYAKNSLPEL SHVKANSTVL NIHIVFEGEK EFHQNVKLWG
VSIHFSDIFW PAYDLQF
//
