ID G3W8E6_SARHA Unreviewed; 557 AA.
AC G3W8E6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=TBCC domain-containing protein 1 {ECO:0000256|ARBA:ARBA00017559};
GN Name=TBCCD1 {ECO:0000313|Ensembl:ENSSHAP00000011701.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000011701.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000011701.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000011701.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Cytoplasm,
CC cytoskeleton, spindle pole {ECO:0000256|ARBA:ARBA00004647}.
CC -!- SIMILARITY: Belongs to the TBCC family.
CC {ECO:0000256|ARBA:ARBA00008848}.
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DR RefSeq; XP_003770221.1; XM_003770173.2.
DR AlphaFoldDB; G3W8E6; -.
DR STRING; 9305.ENSSHAP00000011701; -.
DR Ensembl; ENSSHAT00000011797.2; ENSSHAP00000011701.2; ENSSHAG00000010048.2.
DR GeneID; 100921620; -.
DR KEGG; shr:100921620; -.
DR CTD; 55171; -.
DR eggNOG; KOG4416; Eukaryota.
DR GeneTree; ENSGT00470000042284; -.
DR InParanoid; G3W8E6; -.
DR TreeFam; TF329418; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031616; C:spindle pole centrosome; IEA:Ensembl.
DR GO; GO:0051661; P:maintenance of centrosome location; IEA:Ensembl.
DR GO; GO:0051684; P:maintenance of Golgi location; IEA:Ensembl.
DR GO; GO:0030334; P:regulation of cell migration; IEA:Ensembl.
DR GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
DR Gene3D; 2.160.20.70; -; 1.
DR InterPro; IPR017901; C-CAP_CF_C-like.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR036223; CAP_C_sf.
DR InterPro; IPR006599; CARP_motif.
DR InterPro; IPR039589; TBCC1.
DR InterPro; IPR012945; Tubulin-bd_cofactor_C_dom.
DR PANTHER; PTHR16052:SF0; TBCC DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR16052; UNCHARACTERIZED; 1.
DR Pfam; PF07986; TBCC; 1.
DR SMART; SM00673; CARP; 2.
DR SUPFAM; SSF69340; C-terminal domain of adenylylcyclase associated protein; 1.
DR PROSITE; PS51329; C_CAP_COFACTOR_C; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT DOMAIN 304..438
FT /note="C-CAP/cofactor C-like"
FT /evidence="ECO:0000259|PROSITE:PS51329"
SQ SEQUENCE 557 AA; 63116 MW; 054850351E724C04 CRC64;
MEQSAVHLWV RTEPFIVGTL PLPPPAKFSL HYLRKISTYV RTRAREGGYP RLFWPTWKHI
ACGKLQLAKD IAWLYFEIFD SLVVRTPEER LEWAELISSC VCEEDVEKQR SKLSVDTLQF
LLFLYIQQLN KVSLRTSLIG EEWPSPRNRS PSPDFTGKSI CHNKTWNDCS HQAFVYNHLS
DLLELLLDPE QLSDSSHCTH NSQVCPEAVQ ALSFLIEGTV SKARKVYPIH ELALWQPLHS
ESGFSKISKT FSFSKLEAWL RCCLTANPFG TSACLKTGKK LAWAQQVEGT TKRAKIACNT
HMAPKIHRIV VMTQVYKQTL AKSSETLVGA HVKIHRCNES FIYLLSPLRS VTVEKCRNST
LVLGPVQTSL HLHGCDNVKV IAVCHRLSVS STSGCTFHVL TPTRPLLLAG NQMVTFAPFH
THYPMLEDHM AKNGLATVPN YWDKPMVVCR ENNDARIFRL LPPCEFYVFV IPFEMEGDTT
EIPGGLPPAY QKALGQREQK IQIWQKTVKE AGLTKDQRKQ FQVLVENKFY EWLINTGQSQ
QLDSLVPPAA GSKQAAG
//
