ID G3W8Z4_SARHA Unreviewed; 787 AA.
AC G3W8Z4;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Tubulin tyrosine ligase like 11 {ECO:0000313|Ensembl:ENSSHAP00000011899.2};
GN Name=TTLL11 {ECO:0000313|Ensembl:ENSSHAP00000011899.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000011899.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000011899.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000011899.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3W8Z4; -.
DR STRING; 9305.ENSSHAP00000011899; -.
DR Ensembl; ENSSHAT00000011997.2; ENSSHAP00000011899.2; ENSSHAG00000010211.2.
DR eggNOG; KOG2158; Eukaryota.
DR GeneTree; ENSGT00940000156689; -.
DR HOGENOM; CLU_010131_1_3_1; -.
DR InParanoid; G3W8Z4; -.
DR TreeFam; TF313087; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0036064; C:ciliary basal body; IEA:Ensembl.
DR GO; GO:0070740; F:tubulin-glutamic acid ligase activity; IEA:Ensembl.
DR GO; GO:0051013; P:microtubule severing; IEA:Ensembl.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR004344; TTL/TTLL_fam.
DR PANTHER; PTHR12241; TUBULIN POLYGLUTAMYLASE; 1.
DR PANTHER; PTHR12241:SF154; TUBULIN POLYGLUTAMYLASE TTLL11; 1.
DR Pfam; PF03133; TTL; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR PROSITE; PS51221; TTL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648}.
FT REGION 1..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..774
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..41
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..64
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 787 AA; 89653 MW; F30950CA40FA7ACE CRC64;
MQRACGDGPA DLQAWEDLKA EGEPEPEAKQ NERRPEFELA EPEIEPNADP ESNAEPEPEP
EGEPGPEPES ERPAEAELQP PVPSPAPVTA PNAAEPGDVS NQERRPRPVA RTRTKKGKKG
AGQCASDASR SRRPLTVTVD SSKARTSLDA LKISLRQLKW REFPFGRRLP CDIYWHGVSF
HDNDIFSGQV NKFPGMTEMV RKITLSRAVR IMQDLFPEEY NFYPRSWILP DEFQLFVTQV
RMVKDGDPSW KPTFIVKPDG GCQGDGIYLI KDPSDIRIAG NLQSRPAVVQ EYICKPLLID
KLKFDIRLYV LLKSLEPLEI YIAKDGLSRF CTEPYQEPNF GNLHHVFMHL TNYSLNIHSG
NFIHSDNVNT GSKRTFSSIL CRLSSKGIDI KKIWSDIISL VIKTVIALTP ELKVFYQSDI
PTGRPGPTCF QILGFDILLM RNLKPILLEV NANPSMRIEH EQELSPGVFE NVPSLVDEEV
KVAVIRDTLR LVDPLKNKKK ENRSSDLFTT TSKRKSQGKK SWFQAKRHLL PNVEAGQLSF
QDIFMDRKSR FPSIFGRMSR SKLQFSKFSV VRSEQCNKIS GMREESRTDE ADIFDAETHM
NNEASLPSIC LKQVFPKYAK QFNYLRLVDR MANLFIRFLG IKGTTRLGPT GFRTFIRNCK
LSSSTFSMAS VDILYIDITR RWNSFGLEQK ESGMCLQAFV EAFFFLAQRR FKQSSLQEQV
TSLIDLCEYH LTVLDEKRLL YSKSTSIRPP VINSSQDRLP LTQPPNGSFL PRNNTANKFA
HYRHPHS
//
