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Database: UniProt
Entry: G3WFN7_SARHA
LinkDB: G3WFN7_SARHA
Original site: G3WFN7_SARHA 
ID   G3WFN7_SARHA            Unreviewed;       738 AA.
AC   G3WFN7;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   16-NOV-2011, sequence version 1.
DT   20-JUN-2018, entry version 43.
DE   SubName: Full=SH2B adaptor protein 1 {ECO:0000313|Ensembl:ENSSHAP00000014242};
GN   Name=SH2B1 {ECO:0000313|Ensembl:ENSSHAP00000014242};
OS   Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX   NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000014242, ECO:0000313|Proteomes:UP000007648};
RN   [1] {ECO:0000313|Ensembl:ENSSHAP00000014242}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA   Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E.,
RA   Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q.,
RA   Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A.,
RA   Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S.,
RA   Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y.,
RA   Kreiss A., Woods G.M., Jones M.E., Schuster S.C.;
RT   "Genetic diversity and population structure of the endangered
RT   marsupial Sarcophilus harrisii (Tasmanian devil).";
RL   Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN   [2] {ECO:0000313|Ensembl:ENSSHAP00000014242}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2011) to UniProtKB.
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DR   EMBL; AEFK01080645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 9305.ENSSHAP00000014242; -.
DR   Ensembl; ENSSHAT00000014361; ENSSHAP00000014242; ENSSHAG00000012175.
DR   eggNOG; ENOG410IMWK; Eukaryota.
DR   eggNOG; ENOG41102PH; LUCA.
DR   GeneTree; ENSGT00530000063355; -.
DR   InParanoid; G3WFN7; -.
DR   OMA; GDRWTHR; -.
DR   OrthoDB; EOG091G04RI; -.
DR   TreeFam; TF323184; -.
DR   Proteomes; UP000007648; Unassembled WGS sequence.
DR   GO; GO:0035591; F:signaling adaptor activity; IEA:InterPro.
DR   GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
DR   GO; GO:0045840; P:positive regulation of mitotic nuclear division; IEA:Ensembl.
DR   GO; GO:2000278; P:regulation of DNA biosynthetic process; IEA:Ensembl.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd10346; SH2_SH2B_family; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   Gene3D; 3.30.505.10; -; 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR015012; Phe_ZIP.
DR   InterPro; IPR036290; Phe_ZIP_sf.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   InterPro; IPR030523; SH2B.
DR   InterPro; IPR030521; SH2B1.
DR   InterPro; IPR035057; SH2B1_SH2.
DR   PANTHER; PTHR10872; PTHR10872; 1.
DR   PANTHER; PTHR10872:SF3; PTHR10872:SF3; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF08916; Phe_ZIP; 1.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF109805; SSF109805; 1.
DR   SUPFAM; SSF55550; SSF55550; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007648};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN      524    632       SH2. {ECO:0000259|PROSITE:PS50001}.
SQ   SEQUENCE   738 AA;  78154 MW;  6422471679B8CAB3 CRC64;
     MNGAPSPEDG ASPSPPPLPP PPPPPSWREF CESHARAAAL DFARRFRLYL ASHPQYAGPG
     AEAAFSRRFA ELFLQHFEAE VARASGSLLS SGSIPLSPGT ETPSRDLSLE SCRNSGPLTV
     LGPSRSSEDL AAPLPSSISS SSKPKLKKRF SLRSVGRSVR GSVRGILQWR GAGDPPSPVG
     PLETSASGPP VLGGNSNSNS SGGGGSTNVG PSGGGASPGE RWTHRFERLR LSRGGGPLKE
     GTGTVQREGL LSFMGTEEAA VGGEGRGGGG IGTSSGGGGP PRWQKCRLLL RSEGEGGGNR
     LEFYIPPKAS RPRINILCST ITDVRTTTAL EMPDRENTFV VKVEGSVEYI LETADALNMK
     VWVSDLQDCL SPGPSSPFFS LKFSMPLIPN LMTSFPTREN TDSLDLSCLN HSESLPSQEL
     PLGPSESNEH LSQGAYGGLS DRPSASVSPS SASIAASHFD SMELLPPELP PRVPIEEGPP
     MGTTYPPPAP YPPPDTPDTP EGSFLFQGES DGGDGDHPLS EYPWFHGTLS RLKAAQLVLA
     GGAGSHGVFL VRQSETRRGE YVLTFNFQGK AKHLRLSLNE DGQCRVQHLW FQTVFDMLEH
     FRVHPIPLES GGSSDVTLVS YVVASQRLQE PNISHDPSQP TDPDPRADPA HPGEEEQMVE
     APEAAEQEKA GSGGTPGEPG PVAELEEATA LNREPPGLEG PAGEVGVNPF VHFLQLQPGN
     AGEEGVRSRA INNQYSFL
//
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