ID G3WGC9_SARHA Unreviewed; 756 AA.
AC G3WGC9;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Leucine rich repeat containing 36 {ECO:0000313|Ensembl:ENSSHAP00000014484.2};
GN Name=LRRC36 {ECO:0000313|Ensembl:ENSSHAP00000014484.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000014484.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000014484.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000014484.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3WGC9; -.
DR Ensembl; ENSSHAT00000014606.2; ENSSHAP00000014484.2; ENSSHAG00000012364.2.
DR GeneTree; ENSGT00530000063884; -.
DR HOGENOM; CLU_021289_0_0_1; -.
DR InParanoid; G3WGC9; -.
DR OrthoDB; 2918448at2759; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR23311; HEAT SHOCK REGULATED 2; 1.
DR PANTHER; PTHR23311:SF6; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 36; 1.
DR Pfam; PF14580; LRR_9; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 341..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 702..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 603..681
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 488..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..737
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 756 AA; 85205 MW; 6FE73DECB9424FA1 CRC64;
MAEQWSLDEE VLRRMGALTQ EEPELVESLS LQGSYVGKIH SIGETFKKFK NLRSLDLSRN
LISSLQGIEY LSSLQDLNLY YNNIPSLAEV SRLQALPCLK ELDLRLNPVV RKDTDYRLFA
VHVLQNLEKL DDRVVRDSER KAAKLHFSQL GSNENFLFDV ENKREKTLKN CVMDERSPTK
LETDVDNRIE TELSKGLFLP LPNREIKDSL TSVSSIQASD QDDPKLDTFP LGTQLQEVAR
RELPGDGHQE DEFRCYPSLQ SSVRSPDKMA KEAYRLTFSD DKSIGSSPEK ELISKTDVYQ
LSHEALSSKR LDVGDSSQIH PYQLPKDISL DNYNSHYPHS ITSHGSYSKK SQTHHRSKNY
QDYSTKSLND TKSPSSYSCG DIMTSLSDSD STTGRLLKLS SDLYNTSHFS NESSLLASIE
QQLSVGLADL TQTHGSFTSN AAMGNSLRTF LSQGTQEDRG LLAKRSISPT RRGFKRKDNL
LSSMVPNHSL KDVTNNEPLS SDLGSLHGLQ GNHSPPPIAR TSHVARVLRQ LLELVDKHWN
GSGSLIINKK FLGPARDMLL SLVVPNPSPQ WTRSLPEESL KASRRRDLEL KDVGQFPGIP
NDLEALKQKM VRVLEENLFL SEKVQLLEEN ASNSGVGGHQ SHSYDELLRK NQQLNLQVAC
LNQELNQLKK VEETVHLLQE SQRSLVTTNE YLLQQLNKEQ KNYPGKAVLP PEKSHRVGRT
SPFGKTLQPS LSQTTHDGES SQRERLSEGL ETYMLR
//
