ID G3WM74_SARHA Unreviewed; 281 AA.
AC G3WM74;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=JAML {ECO:0000313|Ensembl:ENSSHAP00000016529.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000016529.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000016529.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000016529.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012400419.1; XM_012544965.1.
DR RefSeq; XP_012400420.1; XM_012544966.1.
DR AlphaFoldDB; G3WM74; -.
DR STRING; 9305.ENSSHAP00000016529; -.
DR Ensembl; ENSSHAT00000016667.2; ENSSHAP00000016529.2; ENSSHAG00000014063.2.
DR GeneID; 100925862; -.
DR KEGG; shr:100925862; -.
DR CTD; 120425; -.
DR eggNOG; ENOG502SVGE; Eukaryota.
DR GeneTree; ENSGT00440000034341; -.
DR HOGENOM; CLU_059564_0_0_1; -.
DR InParanoid; G3WM74; -.
DR TreeFam; TF331728; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013106; Ig_V-set.
DR InterPro; IPR000920; Myelin_P0-rel.
DR PANTHER; PTHR13869:SF22; JUNCTIONAL ADHESION MOLECULE-LIKE; 1.
DR PANTHER; PTHR13869; MYELIN P0 RELATED; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..281
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5029895642"
FT TRANSMEM 158..177
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..126
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 246..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..264
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 281 AA; 31964 MW; E621EB9A4BF1B434 CRC64;
MFYPLELKLL SMLLGCVWGL DDMVVSSPEM MAHVGDSALL GCILPSAVKK QVTKVNWMFS
AGEYAEEEFV LYYYANLSVP VGNFKDRVHL VGKISDNDGS ILLQDLREAD QGVYTCEIQI
HKESLVFKKT TMLKVVPAKP TTMKPTFRTD VLSNYQQVII VGIVCFTILL LAVLGVTMRR
RQRSHRSENH LENTSKANPE VQAHVYSTVT TQSVTEEEES NRAEATYMTM QPVWPSWRAE
QNKSFERMPE TEQTFERPRF AIRPLTKEDN GSQKPLIPHL S
//
