ID G3WN20_SARHA Unreviewed; 1169 AA.
AC G3WN20;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Tudor domain containing 1 {ECO:0000313|Ensembl:ENSSHAP00000016825.1};
GN Name=TDRD1 {ECO:0000313|Ensembl:ENSSHAP00000016825.1};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000016825.1, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000016825.1, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000016825.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3WN20; -.
DR Ensembl; ENSSHAT00000016967.2; ENSSHAP00000016825.1; ENSSHAG00000014311.2.
DR GeneTree; ENSGT00940000158754; -.
DR HOGENOM; CLU_010832_0_0_1; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20408; Tudor_TDRD1_rpt1; 1.
DR CDD; cd20409; Tudor_TDRD1_rpt2; 1.
DR CDD; cd20410; Tudor_TDRD1_rpt3; 1.
DR Gene3D; 2.30.30.140; -; 4.
DR Gene3D; 2.40.50.90; -; 4.
DR Gene3D; 6.10.140.2220; -; 1.
DR InterPro; IPR035437; SNase_OB-fold_sf.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR047376; Tudor_TDRD1_rpt1.
DR InterPro; IPR047377; Tudor_TDRD1_rpt2.
DR InterPro; IPR047378; Tudor_TDRD1_rpt3.
DR InterPro; IPR002893; Znf_MYND.
DR PANTHER; PTHR22948; TUDOR DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF00567; TUDOR; 4.
DR Pfam; PF01753; zf-MYND; 1.
DR SMART; SM00333; TUDOR; 4.
DR SUPFAM; SSF144232; HIT/MYND zinc finger-like; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 4.
DR PROSITE; PS50304; TUDOR; 4.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00134}.
FT DOMAIN 162..198
FT /note="MYND-type"
FT /evidence="ECO:0000259|PROSITE:PS50865"
FT DOMAIN 306..366
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 536..595
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 758..817
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT DOMAIN 981..1039
FT /note="Tudor"
FT /evidence="ECO:0000259|PROSITE:PS50304"
FT REGION 444..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 453..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1169 AA; 131949 MW; 438055F8FC7D92F1 CRC64;
MSRNNSDISA CKVTEQLNIE RNEIKPPHEP LRSPRSYPNF KLKSPEHGSK TVGIAKKNFL
FCEQTKRYFA SCENSSPPSN SNCINKEAVG SKIDKKTSTG NSVATLNIGN NLPTKELNTK
LSTHLSPAKP KMLQNLSENP LSLNYDSKLF NSLIPSPRST TCHRCGLYGS LRCSQCKQTY
YCCVACQRRD WSAHSIVCKP IKQNFPKPDD TKLSCETKKM EVNKEDDYQL GITTEIIGST
KKIMFSDLQN LQLRKTMEIK GTVTEFKHPG EFYIQICSSE VLEYIRKLST SLKESYMNMM
PQEEYIPIKG EICVAKYSVD QTWNRVIVQD VDVQQKKAQV LYIDYGNGEV IPISRIQQLN
KNIELFPPCA IKCFVANVIP AEGSWNNDCT NAIKPLLVEQ YCSLKILDIL QEEIISFAVD
VLLPGSGKHL DHVLLEMGYG LRPKGQNSKM QSSDKSDFED SGEKTSKDKT TTECKSNLIP
KVLSLNVGDE FCGVVAHIQT PEDFFCQQLQ SGRQLAELQL SLSEYCNKMS TQSDFYPAIG
DICCAQFSED NQWYRASVLA YASEESALVG YVDYGNFEIL KLNRLCPMAP RLLELPMQAI
KCILAGVKPS SGIWSPEAIC LMKKLIRNKM ITVKVVDKKE NSSVVELIDK SIKPSISVSK
ILIEAGFAVG EGKILTTDTS NELREINAPL TVEETVNTFE WTWVELAVNE TVNVMVCMLY
NPGEFYCHIL KEDALSGLNE VNRSLAEYCQ QKMPNEFKPE IGEPCCAYFT GDGNWYRALV
KEILPNATVK VHFVDYGNIE EVTVDKLRKM SSKFLKLPFQ GIRCWLVDIK PRNKHWSKEA
TARFQMCVAG IKLKAKIVDL TDNGAGVELT DPSTAYPKII SDILIDEHLV LKDEPPCKDT
QNSKPVDLPF DPDVLQATSS DQWKTIEFPV DEIVPACILE IISPSLFYAL PIESRDQEKL
NLMTVKLTDH CNSQKNRALF KPRIGDVCCA RFTSDNYWYR AIILKVSESE VKVLYADYGN
IETLPFSRIQ PITTIYLELP FQIIRCSFEG IMELEGGWSP LVLEQLKKLM LNQNVMISVK
GIIKNVHAVS VEKRSENGTI NIADKLVMEG LAKHIATKNQ SVLNKGQTNC CCTELRKQVE
KHEQILLFLL NNPTNQDKFT EMKKLLKIK
//
