ID G3WQG1_SARHA Unreviewed; 706 AA.
AC G3WQG1;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSSHAP00000017666.2};
GN Name=TTC12 {ECO:0000313|Ensembl:ENSSHAP00000017666.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000017666.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000017666.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000017666.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3WQG1; -.
DR STRING; 9305.ENSSHAP00000017666; -.
DR Ensembl; ENSSHAT00000017811.2; ENSSHAP00000017666.2; ENSSHAG00000014998.2.
DR eggNOG; KOG0548; Eukaryota.
DR GeneTree; ENSGT00940000164257; -.
DR HOGENOM; CLU_391258_0_0_1; -.
DR InParanoid; G3WQG1; -.
DR TreeFam; TF332406; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR043195; TTC12.
DR PANTHER; PTHR46540; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR PANTHER; PTHR46540:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 12; 1.
DR Pfam; PF00515; TPR_1; 2.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 176..209
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT COILED 3..59
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 706 AA; 79298 MW; FCB1E58239DEEBDC CRC64;
MAKEKEERDL EKFLKNVDEI STLVQDLNSD DFDVCERAMD EAEKRLQLQE DQEEDECRTI
LNKTMISPPQ VPTEQVDVDD TNPDGFMKIL EKDARERAKR RKENKSLANA FKEKGNEAFL
KGDYEMAVHY YTEGLKKLKD MKVLYTNRAQ AYMKLEEYEK ALVDCEWALK CDENSTKAYF
HMGKAHLALK NYSMARQCYQ KILEINPKLQ VQVKDSLNKV DQKEKAELQE KLALQELKSG
KEAAVTTKNL LEALSNPEQI PLFYAGGVQL LTELMEDCTE KTLFRTHNGF SIINDNKVIK
RCFATEEKDE IEEILCIAVL KLWHAVCTGN EENQHLLLAH SDMDILLPAF LTSKVPSIQQ
HTLSLLLLFC QTENGRILVL SHMDLARLLQ ALVLFVNISE EKESRTAMQL LTDLALEERF
KTLVQTNLPA LLTLISILNI PEIAYPSTLL QCVAIMGNLS TDATIRKQMS DCEECWDACF
RLMAKCEENV TLFRETLYAT LGFMMNLSLE SVSITEVLAE QVSRKCVSLL NSEDGGILTR
AAGVLSRVLS ASMKAVEEAV QAGLMKVMIK FLKAGGQTAS RYAIKILAVC TNINYLAREE
VTRLDKKFCL LIKLLEAEDE IIAGNAALCI GNCVEVPGAS SAVLKSDIVK ILLKLAGGDA
KEASVQLNAG IALGKLCTAE PRHTAHLEEL HGIEILNSTM KYIQKS
//
