ID G3WRX6_SARHA Unreviewed; 207 AA.
AC G3WRX6;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Rab interacting lysosomal protein like 2 {ECO:0000313|Ensembl:ENSSHAP00000018181.2};
GN Name=RILPL2 {ECO:0000313|Ensembl:ENSSHAP00000018181.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000018181.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000018181.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000018181.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; G3WRX6; -.
DR STRING; 9305.ENSSHAP00000018181; -.
DR Ensembl; ENSSHAT00000018331.2; ENSSHAP00000018181.2; ENSSHAG00000015435.2.
DR eggNOG; ENOG502S08B; Eukaryota.
DR GeneTree; ENSGT00940000160182; -.
DR HOGENOM; CLU_096533_1_0_1; -.
DR InParanoid; G3WRX6; -.
DR TreeFam; TF313489; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:GOC.
DR GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0003382; P:epithelial cell morphogenesis; IEA:Ensembl.
DR GO; GO:1903445; P:protein transport from ciliary membrane to plasma membrane; IEA:Ensembl.
DR CDD; cd14445; RILP-like; 1.
DR Gene3D; 1.20.58.1770; -; 1.
DR Gene3D; 6.10.230.10; -; 1.
DR InterPro; IPR034743; RH1.
DR InterPro; IPR034744; RH2.
DR InterPro; IPR021563; RILP_dimer.
DR Pfam; PF11461; RILP; 1.
DR SUPFAM; SSF161256; RILP dimerisation region; 1.
DR PROSITE; PS51776; RH1; 1.
DR PROSITE; PS51777; RH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 15..102
FT /note="RH1"
FT /evidence="ECO:0000259|PROSITE:PS51776"
FT DOMAIN 126..194
FT /note="RH2"
FT /evidence="ECO:0000259|PROSITE:PS51777"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 68..102
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 207 AA; 23490 MW; 50F39D78A5C3039A CRC64;
KKPSPEKEGG EGRRGDPQNP GKNPFHLTAE DVYDISYVVG RDLMAITGDS RDVATRVTQL
QFKIVRILEM LEALVNDCNV TVEELRMERD SLRKEVEGLR SEGHASFPEV NPGTNKVVVD
LTDPNRPRFT MQELRDVLHE RNKLKSQLLV AQEELQCYKS GLIPPNNSQM ARRDPEALIT
STTNSKEGKQ EKTIIRKLFS FRSGKRT
//
