ID G3WTP3_SARHA Unreviewed; 410 AA.
AC G3WTP3;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 16-NOV-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Methyltransferase like 15 {ECO:0008006|Google:ProtNLM};
GN Name=METTL15 {ECO:0000313|Ensembl:ENSSHAP00000018798.1};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000018798.1, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000018798.1, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000018798.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. RsmH family.
CC {ECO:0000256|ARBA:ARBA00010396}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_003773699.1; XM_003773651.2.
DR AlphaFoldDB; G3WTP3; -.
DR STRING; 9305.ENSSHAP00000018798; -.
DR Ensembl; ENSSHAT00000018953.2; ENSSHAP00000018798.1; ENSSHAG00000015956.2.
DR GeneID; 100932985; -.
DR KEGG; shr:100932985; -.
DR CTD; 196074; -.
DR eggNOG; KOG2782; Eukaryota.
DR GeneTree; ENSGT00390000014756; -.
DR OMA; SICVKEI; -.
DR OrthoDB; 230623at2759; -.
DR TreeFam; TF106425; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.170; Putative methyltransferase TM0872, insert domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_01007; 16SrRNA_methyltr_H; 1.
DR InterPro; IPR002903; RsmH.
DR InterPro; IPR023397; SAM-dep_MeTrfase_MraW_recog.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00006; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH; 1.
DR PANTHER; PTHR11265:SF0; 12S RRNA N4-METHYLCYTIDINE METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11265; S-ADENOSYL-METHYLTRANSFERASE MRAW; 1.
DR Pfam; PF01795; Methyltransf_5; 1.
DR SUPFAM; SSF81799; Putative methyltransferase TM0872, insert domain; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 42..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 45697 MW; E8DAC14534A70CFA CRC64;
MLRYQYFCRI YRGFFPYNFG TGILNIGRCP KEMHSSVSRY NELKDEEHAS VSKDQEMHHS
QSGNLETMKQ LHIPVMVNEV IDCLAPQPGQ NILDMTFGSG GHSRAILQKE VDVTLYVLDR
DPTAYAIAQQ LSELYPKQIR ALLGQFSQAE AMLIKAGVQP GTVDGVLLDL GCSSMQLDTP
ERGFSFRKDG PLDMRMDGGR YPDMPTAADV VNALDQQALA LILRTYGEEK SAKKIASAIV
QARRIYPITR TQQLASIVAG AFPSGALYGR KDLLQRPTHI ATKTFQALRI FVNNELNELY
AGLQTAQKFL RPGGRLVTLS FHSLEDRLVK RFLLGADVAA KPGPRRRQRE RSASALWPSP
DREQEPGGSS APKDWEMVRK KVVTPEDSEL LSNPRGRSAK LRAAVRLQGP
//
