ID G3X2T0_SARHA Unreviewed; 480 AA.
AC G3X2T0;
DT 16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT 07-APR-2021, sequence version 2.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=F-box protein 3 {ECO:0000313|Ensembl:ENSSHAP00000021985.2};
GN Name=FBXO3 {ECO:0000313|Ensembl:ENSSHAP00000021985.2};
OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus.
OX NCBI_TaxID=9305 {ECO:0000313|Ensembl:ENSSHAP00000021985.2, ECO:0000313|Proteomes:UP000007648};
RN [1] {ECO:0000313|Ensembl:ENSSHAP00000021985.2, ECO:0000313|Proteomes:UP000007648}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21709235; DOI=10.1073/pnas.1102838108;
RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., Miller J.,
RA Walenz B., Knight J., Qi J., Zhao F., Wang Q., Bedoya-Reina O.C.,
RA Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., Woodbridge P.,
RA Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., Helgen K.M.,
RA Lesk A.M., Pringle T.H., Patterson N., Zhang Y., Kreiss A., Woods G.M.,
RA Jones M.E., Schuster S.C.;
RT "Genetic diversity and population structure of the endangered marsupial
RT Sarcophilus harrisii (Tasmanian devil).";
RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011).
RN [2] {ECO:0000313|Ensembl:ENSSHAP00000021985.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
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DR AlphaFoldDB; G3X2T0; -.
DR STRING; 9305.ENSSHAP00000021985; -.
DR Ensembl; ENSSHAT00000022161.2; ENSSHAP00000021985.2; ENSSHAG00000018609.2.
DR eggNOG; KOG4408; Eukaryota.
DR GeneTree; ENSGT00940000153571; -.
DR HOGENOM; CLU_056869_0_0_1; -.
DR TreeFam; TF329795; -.
DR Proteomes; UP000007648; Unassembled WGS sequence.
DR CDD; cd22084; F-box_FBXO3; 1.
DR Gene3D; 1.20.1280.50; -; 1.
DR Gene3D; 2.60.40.1470; ApaG domain; 1.
DR InterPro; IPR007474; ApaG_domain.
DR InterPro; IPR036767; ApaG_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR018958; Knr4/Smi1-like_dom.
DR InterPro; IPR037883; Knr4/Smi1-like_sf.
DR PANTHER; PTHR46550; F-BOX ONLY PROTEIN 3; 1.
DR PANTHER; PTHR46550:SF1; F-BOX ONLY PROTEIN 3; 1.
DR Pfam; PF04379; DUF525; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF09346; SMI1_KNR4; 1.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00860; SMI1_KNR4; 1.
DR SUPFAM; SSF110069; ApaG-like; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR SUPFAM; SSF160631; SMI1/KNR4-like; 1.
DR PROSITE; PS51087; APAG; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007648};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 15..61
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT DOMAIN 302..432
FT /note="ApaG"
FT /evidence="ECO:0000259|PROSITE:PS51087"
FT REGION 434..480
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..459
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 480 AA; 54730 MW; D9A7DC2534A4E399 CRC64;
MAAAAAAALG AEEPELCLEL LPTDPLLLIF SFLDYQDLVS CSCVSRRLNQ LSNHDPLWRR
HCKKYWLLSE AEKTQKNKSW KTLFKDTYID LGRYIQHYAT LKKAWDDLER YLGQRCPRMI
GSLKDSVEEC ELDAVEAQIG CKLPNDYRCS FRIHNGQKLV VPGLMGSMAL SNHYRSEDLL
DIDTAAGGFQ QRQGLKQCLP LTFCIHTGLS QYMALESVEG RNKYEIFYQC PDQMARNPSA
IDMFITGWRG NLRAKAVLST VPDTHSASYS EWFTSYVHNV VTGGYPIIRD QIFRYVHDKG
CVATTGDITV SVSTSFLPEL SSVHPPHYFF TYRIRIEMSK DALPEKTCQL DSRYWRITNA
KGEIEEVQGP GVVGEFPILS PGRVYEYTSC TTFSTTSGYM EGHYTFHLLY YKDRIFNVAI
PRFHMVCPTF KVSTTPRETS HDDCSVIEED EEEDSTDSDD YEGPRLVNYS PAPSHCPRHT
//
