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Database: UniProt
Entry: G3X6V2_BOVIN
LinkDB: G3X6V2_BOVIN
Original site: G3X6V2_BOVIN 
ID   G3X6V2_BOVIN            Unreviewed;       619 AA.
AC   G3X6V2;
DT   16-NOV-2011, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 2.
DT   26-FEB-2020, entry version 46.
DE   RecName: Full=Dihydroxyacetone phosphate acyltransferase {ECO:0000256|PIRNR:PIRNR000437};
DE            Short=DAP-AT {ECO:0000256|PIRNR:PIRNR000437};
DE            Short=DHAP-AT {ECO:0000256|PIRNR:PIRNR000437};
DE            EC=2.3.1.42 {ECO:0000256|PIRNR:PIRNR000437};
GN   Name=GNPAT {ECO:0000313|Ensembl:ENSBTAP00000014266,
GN   ECO:0000313|VGNC:VGNC:58355};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913 {ECO:0000313|Ensembl:ENSBTAP00000014266, ECO:0000313|Proteomes:UP000009136};
RN   [1] {ECO:0000313|Ensembl:ENSBTAP00000014266}
RP   IDENTIFICATION.
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000014266};
RG   Ensembl;
RL   Submitted (MAR-2016) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSBTAP00000014266, ECO:0000313|Proteomes:UP000009136}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford {ECO:0000313|Ensembl:ENSBTAP00000014266,
RC   ECO:0000313|Proteomes:UP000009136};
RA   Rosen B.D., Bickhart D.M., Koren S., Schnabel R.D., Hall R., Zimin A.,
RA   Dreischer C., Schultheiss S., Schroeder S.G., Elsik C.G., Couldrey C.,
RA   Liu G.E., Van Tassell C.P., Phillippy A.M., Smith T.P.L., Medrano J.F.;
RT   "ARS-UCD1.2.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=an acyl-CoA + dihydroxyacetone phosphate = a 1-acylglycerone
CC         3-phosphate + CoA; Xref=Rhea:RHEA:17657, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57534, ChEBI:CHEBI:57642, ChEBI:CHEBI:58342; EC=2.3.1.42;
CC         Evidence={ECO:0000256|PIRNR:PIRNR000437};
CC   -!- PATHWAY: Membrane lipid metabolism; glycerophospholipid metabolism.
CC       {ECO:0000256|PIRNR:PIRNR000437}.
CC   -!- SUBCELLULAR LOCATION: Peroxisome membrane
CC       {ECO:0000256|PIRNR:PIRNR000437}; Peripheral membrane protein
CC       {ECO:0000256|PIRNR:PIRNR000437}; Matrix side
CC       {ECO:0000256|PIRNR:PIRNR000437}.
CC   -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC       {ECO:0000256|PIRNR:PIRNR000437}.
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DR   PaxDb; G3X6V2; -.
DR   Ensembl; ENSBTAT00000014266; ENSBTAP00000014266; ENSBTAG00000010773.
DR   VGNC; VGNC:58355; GNPAT.
DR   eggNOG; KOG3730; Eukaryota.
DR   eggNOG; COG2937; LUCA.
DR   GeneTree; ENSGT00520000055570; -.
DR   HOGENOM; CLU_017332_0_1_1; -.
DR   InParanoid; G3X6V2; -.
DR   TreeFam; TF313360; -.
DR   UniPathway; UPA00940; -.
DR   Proteomes; UP000009136; Chromosome 28.
DR   Bgee; ENSBTAG00000010773; Expressed in testis and 9 other tissues.
DR   ExpressionAtlas; G3X6V2; baseline and differential.
DR   GO; GO:0031966; C:mitochondrial membrane; IBA:GO_Central.
DR   GO; GO:0005778; C:peroxisomal membrane; IBA:GO_Central.
DR   GO; GO:0016287; F:glycerone-phosphate O-acyltransferase activity; IBA:GO_Central.
DR   GO; GO:0008611; P:ether lipid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR   GO; GO:0006650; P:glycerophospholipid metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IBA:GO_Central.
DR   CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR   InterPro; IPR028353; DHAPAT.
DR   InterPro; IPR022284; GPAT/DHAPAT.
DR   InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   PANTHER; PTHR12563; PTHR12563; 1.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   PIRSF; PIRSF500063; DHAPAT; 2.
DR   PIRSF; PIRSF000437; GPAT_DHAPAT; 1.
DR   SMART; SM00563; PlsC; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|PIRNR:PIRNR000437};
KW   Membrane {ECO:0000256|PIRNR:PIRNR000437};
KW   Peroxisome {ECO:0000256|PIRNR:PIRNR000437};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009136};
KW   Transferase {ECO:0000256|PIRNR:PIRNR000437}.
FT   DOMAIN          95..224
FT                   /note="PlsC"
FT                   /evidence="ECO:0000259|SMART:SM00563"
SQ   SEQUENCE   619 AA;  70440 MW;  08E988BC05142FC2 CRC64;
     MDHSSSSNSC FSVGSTSPGA VVLLYSLSKE SLQPVEVLRE EACEILDEMS HKLRLGAIRF
     FAFALSKIFK QIFSKVRVNE EGIQKLQRAI QEHPVVLLPS HRSYIDFLML SFLLYNYDLP
     VPVIAAGMDF LGMKMVGELL RMSGAFFMRR TFGGNKLYWA VFSEYVKTML RNGYAPVEFF
     LEGTRSRSAK TLTPKFGLLN IVMEPFFKRE VFDTYLVPIS ISYDRILEET LYAYELLGVP
     KPKESTTGLL KARRILSEKF GNIHVYFGDP VSLRSLAAGR MGRSPYNLVP RYIPQKQSEE
     MHTFVTEVAY KMQLLQIQNL VLSPWPLIVA VLLQNRPSMD FDALLEKTLW LKGLTQAFGG
     FLTWPDNEPA EAVIQSSILL HSNIVSLVKD RVILKMECGD SELVDGLIFQ HITLLMCLAY
     RNQLLNVFVR PSLVAMALQM TPGFRKEDVY SCFRFLCSVF SDEFIFLPGN ALKDFEEGCY
     LLCKSEAIQV MTRDILVTEK GNSVLEFLIG LFKPFVESYQ IICKYLLNEE EDYFTEKQYF
     IRVRKFTSQL LDQGASQCYD VLSSDVQKNA LAAFVRLGVV EKKKVNNDYI FNVNEPATTK
     LEEMLGCKTP VGKPATAKL
//
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