ID G3XMF3_ASPNA Unreviewed; 1116 AA.
AC G3XMF3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=DNA repair protein rad5 {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPNIDRAFT_212656 {ECO:0000313|EMBL:EHA28266.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA28266.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA28266.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA28266.1}.
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DR EMBL; ACJE01000001; EHA28266.1; -; Genomic_DNA.
DR AlphaFoldDB; G3XMF3; -.
DR STRING; 380704.G3XMF3; -.
DR HOGENOM; CLU_000315_2_5_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd18008; DEXDc_SHPRH-like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014905; HIRAN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45626:SF22; DNA REPAIR PROTEIN RAD5; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08797; HIRAN; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00910; HIRAN; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 452..650
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 838..883
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 942..1098
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 330..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 896..921
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 904..919
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1116 AA; 125477 MW; CB6B93719CFB7410 CRC64;
MDDSTRVEDH AVPHVEQEIV QAEHHNADSR TEGALLQVDY DGFDITTFTS IIGENLSADS
IQRIRSAAGD DLERAVNIYF DGSWKKSPTP RAQNQTTLTA RQRPLPTQPH KIATPLSAAC
KPHTQTLPPD KVTSRPATQP PLRYIGAFGV GAWATRSGAG FLRHGDLVNI ERTRSQPLSK
RNRAGKLVSN QKSDVLTRFT TKSGQEIGRL PRETAEWVST LLDQRVCTFE GVCVYVPDRV
RVNDTIYLQL RCYLRIEAFQ PRIFSQSMDD NRSVAIFEEK ESADEKALRL RQVALVKLFD
EIHLQPTSVN DMTRNHKKEG LLRAAEMAEQ HERVKKENQT NDDSSEEDSP ELEEDQLDTL
YKKAQSFDFS MPEAEPASSF TLHLRKYQRQ ALYWMLAKEK DNKSARETSL HPLWEEYSWP
SRDVDDKELP VVAGIDHFYV NPYSGELSLD FPVQEQHCLG GILADEMGLG KTIEMLSLVH
SHRIMPQKPT DLVRLPQSAS GVVPAPYTTL VIAPTSLLSQ WESEALKASQ PGTMNVLMYY
GADKNINLKN LCASGNAAAP NLIITSYGVV LSEYRQHMSA LLSSMSSGGL FSVDFFRVIV
DEAHVIKNRL SKTAKACYEL KATHRWVLTG TPIVNRLEDL FSLVRFLKVE PWNNFSFWKT
FITVPFESKD YVRALNVVQS VLEPLVLRRT KTMKTPEGEP LVPLPRRTIT IEEVELPDQE
REIYDLIFTR AKQTFNHNVE AGTLLKSYST IFAQILRLRQ TCCHPILTRN KAIVADEEDA
AAAADAANDL KDDMDLQDLI DRFKASTEAA ESNEPQDPSA KFTAHALKQI QNEASGECPI
CSEEPMIDPA VTACWHSACK KCLEDYIRHQ TDKGMDPRCF SCRAPTTSRD IFEVVRHESP
NTTPEDDIYS STPTPSQAPP RISLRRIHPL SPSAHTSAKV HALLAHLARV PANTKSVVFS
QFTSFLDLIS PQLTRAGIHH VRLDGTMPHK ARAETLAQFN RHRHSTAPPP PTVLLISLRA
GGVGLNLTAA SNVFMMDPWW SFAIEAQAID RVHRMGQTRD VQVTRFVVKD SIEGRMLRVQ
ERKMNIAGSL GLRVGGDGSE DDKKKERIEE LRLLFE
//
