ID G3XQV2_ASPNA Unreviewed; 747 AA.
AC G3XQV2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Choline kinase N-terminal domain-containing protein {ECO:0000259|Pfam:PF04428};
GN ORFNames=ASPNIDRAFT_205603 {ECO:0000313|EMBL:EHA26900.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA26900.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA26900.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- PATHWAY: Phospholipid metabolism. {ECO:0000256|ARBA:ARBA00025707}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA26900.1}.
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DR EMBL; ACJE01000004; EHA26900.1; -; Genomic_DNA.
DR AlphaFoldDB; G3XQV2; -.
DR STRING; 380704.G3XQV2; -.
DR HOGENOM; CLU_012712_4_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR007521; Choline_kin_N.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF93; RE24176P; 1.
DR Pfam; PF04428; Choline_kin_N; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
FT DOMAIN 200..271
FT /note="Choline kinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04428"
FT REGION 1..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 173..213
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..89
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 747 AA; 84036 MW; FE08035B05060EA3 CRC64;
MDSDRSSKGP QPILGTGLNV SPQRHHHTNG HETSAIASEG TAFRHRVSAP KKPAARLPTH
QPASLSSQTS SVITEPAHRH ERDGISKNGE EDPQNSLFAQ VYEWLQREKS KRRSHKATSL
ATMDGVASDG DDDDDDSASV LVERPLSSGA DTTMALDKLE KILIQYATSR QGTDSVHLTR
RSGRRRQYSK GLRRGSASES DFSDHEAAAP SVDAVLDNSK TLAYSGGGTE DDDNENSVNA
RRAKDKEAWT LFKSEILRLA HTMQLKGWRK LPMELATDIG VVRLSGALTN AVYVVTPPQN
IPVPKAEDGS YSLVPRKPPP KLLLRIYGPQ VDHLIDRDNE LQILRRLGRK NIGPKVLGTF
NNGRFEEYFE ARPLTPKELR DPPTMKQIAK RMRELHDGID LLVDEREGGP MVFKNWDKWV
DRCEQVINWL DKEIRSEHNK SKAASEAWRR RGFVCGVPWP SFRKAVEGYR KWLLSSCGGM
DGIKRQLVFA HNDTQYGNLL RMEPSHESPL LRPENVHKQL VVIDFEYASA NTPGIEFANH
FTEWCYNYHD PERPWACDTS RYPNPEQQHQ FIEAYLSHRP GLREQASPSI TPLMRGLSTN
TSSLAPLSLD DGPDVDVSAR FDIEKAHEDS TSAKIQYYAR QTRLWRVLNS AQWVAWGIVQ
AKVPGMEEGI AADEAAAKAQ NGHHVNHSTG TPPVDADVDE AEEFDYLGYA QDRAMFFWSD
LLALKIIRED ELPESLVHVI KSRMIDY
//
