ID G3Y3F2_ASPNA Unreviewed; 1240 AA.
AC G3Y3F2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 22-FEB-2023, entry version 55.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=ASPNIDRAFT_52269 {ECO:0000313|EMBL:EHA22997.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA22997.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA22997.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA22997.1}.
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DR EMBL; ACJE01000010; EHA22997.1; -; Genomic_DNA.
DR AlphaFoldDB; G3Y3F2; -.
DR STRING; 380704.G3Y3F2; -.
DR HOGENOM; CLU_003256_2_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT DOMAIN 309..553
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 965..998
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 859..894
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1165..1240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 872..891
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1240 AA; 137712 MW; B5845F2DDBB65B0B CRC64;
MPTETPEQLT NGNHPEETQE EDNTGGLFQI TVKLPHEPYK IQVMVSSQEQ VQDVRQSIVE
LPSTFQYTCF HLEFNGQRIN DFVELSEVPD LKADSEITLV EDPYNEKEAR MHVVRMRELV
GAAGDRVDNL HGISAGLSLH DAISAEVADA SEKEHSLSKY DITSSPSLKT ILPRAEAPLP
KTVKAISLSP WNPVPYHLRQ KGHLLYLQVT TNEGEQFQIT SHISGFYVNK NSNMKFDPSP
KTIPKSGRAH SLLTLIAHLS PSFNASFEAL QESNNKKDLL TTFPFQNAIP NNPWLVPPPT
STANAHQPDI TRSQENYLIS GVDNAETLRD WNEEFQTTRE LPRETVQDRV FRERLTSKLF
ADYNEAAARG AVLVARGEVA PLNPTESRDA QIFVYNNIFY SFGADGVGTF ASEGGDEAAR
VAVGKDVVGI KAVNQLDING LFTPGTVVVD YLGKRIVGQS IVPGIFKQRE PGEHQIDYGG
VEGKDVVATH PDFVSVFEKM SKALRVKKHA VWDKEGQRHE LEGSVETKGL LGTDGRKYVL
DLYRVTPLDV MWQEEEGSDA YPHRMSVLRL ELVESYWRHK MSQYVKAEVE RRRSAKAEAD
AAKAESSEAT ESKEQASEEK SEEDQERVDI SGFSLALNPD VCSGQVPQTD EEKEQWAQDE
KEVRETCDYL RSKIMPELIQ DLHDGDVGFP MDGQSLSQLL HKRGINIRYL GKLAQLSKEK
GSRLDALSTL LVQEMIARAF KHIANEYLRN VPAPFVASCI SHLLNCLLGA DVNPNPVAEI
DASLRSIYPE GDFSFEKATP ATLRAAIEKQ VTIRYRFTLE AEWFNSLRHL QLLRDLSIKL
GLQLGAREFI FDKSQIPAKA PATNGANGVA QEEGKNKKKK KGGDSSSPAR AAKEEKPILA
IVPDDILNIV PLVKDASPRS SLAEEALEAG RISLMQNQKQ LGQELILESL SLHEQIYGIL
HPEVAKLYHQ LSMLYYQTDE KEAAVELARK AVIVTERTLG VDSADTILSY LNLSLFEHAS
GNTKTALAYI KHAMDLWKII YGANHPDSIT TMNNAAVMLQ HLKQYSDSRK WFEASLEVCE
SLFGRQSINT ATILFQLAQA LALDQDSKGA VGKMRDAYNI FLSQLGPNDR NTKEAETWLE
QLTQNAVSIA KHAKDIQARR LRRVNMNPRS LGTKIQPQVG QTAPEVAGAR APGSASLDSR
SVDELLKFIE GGDAGSSKAK QKKRAAASNP KLRGSKKSSA
//
