ID G3YGE3_ASPNA Unreviewed; 1279 AA.
AC G3YGE3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=5-oxo-L-prolinase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPNIDRAFT_55671 {ECO:0000313|EMBL:EHA18624.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA18624.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA18624.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- SIMILARITY: Belongs to the oxoprolinase family.
CC {ECO:0000256|ARBA:ARBA00010403}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA18624.1}.
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DR EMBL; ACJE01000021; EHA18624.1; -; Genomic_DNA.
DR AlphaFoldDB; G3YGE3; -.
DR STRING; 380704.G3YGE3; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1169197; -.
DR HOGENOM; CLU_002157_0_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR003692; Hydantoinase_B.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR Pfam; PF02538; Hydantoinase_B; 1.
PE 3: Inferred from homology;
FT DOMAIN 9..215
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 234..534
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 545..717
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
FT DOMAIN 740..1276
FT /note="Hydantoinase B/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF02538"
SQ SEQUENCE 1279 AA; 138540 MW; 82AA57663B000F9B CRC64;
MPGSDKITIS IDRGGTFTDV HAVVPGRPDI ILKLLSVDPG HYQDAPTEGI RQILELVTGE
SHPRGQPLKL DRIGSLRMGT TVATNALLER KGARSVLLTT KGFRDLLKIG DQSRPNIFDL
SMARPGVLPE QVVEINERVV PCHPLADKDC FKNARIVEGT TGEKFRVVQE LDIEEVRPVL
QQLKEKGYQS LSVALVHSFA YPEHERIIGE LAESMGFSVT LSSKLQPMIK VVPRGMSAAA
DAYLTPVIKT YIDSISASFE GGLEKQHECR FEFMQSDGGL VDFRRFSGLK AILSGPAAGV
VGFAATSWDP EEKTPVIGFD MGGTSTDVSR FDGHLEHVFG SKVAGVLIQS PQLDINTVAA
GGGSILSWRN GLFYVGPESA SAHPGPACYR KGGPLTVTDA NLFLGRLLPE YFPHIFGPNE
DQPLDIEITT KLFNELTQKI NTERKEKGQS EFTAEEVALG FLKVADESMA RPIRNLTEAR
GFETASHHLA CFGGAGGQHA CTVAASLGIS RVIIHKFSSV LSAYGLALAE VVKESQEPVS
TEYSTSQSTL DKRFEAMIKA STEDMQEQGF SADQVRHDLY LNLRYEGSDT SLMILKPEDD
SDFLEQFRAR HRREFGFNSD RAVLVDDIRV RTIACSKVRT EKSPLVQLRE ATLKDVSGGP
DNISKAYFDG QSERIDTPVY LLDKLEKNTR VHGPAVIIDE TQTVVVAPNA VASILETCIV
IDLEELPNVN GIEGGSSGID PIRLSIFGHR FMSIAEQMGR TLQKTSVSTN IKERLDFSCA
LFSPDGGLVA NAPHVPVHLG SMQFAVRYQH QKWLGNLHDG DVLVANHPSS GGTHLPDITV
ITPVFDRPGG TEIMFYVASR GHHADIGGIL PGSMPPKSTE LWQEGAAIEG DKIVSNGVFD
EERMMELLVH KPAQYEGCSG ARCVSDNLSD LKAQIAANTR GITLIQALFA EYGVETVQKY
MYAIQATAET AVRNLLKDLH KKFGGQPLEA VDYMDDGTPI KLKVTINGSD GSAVFDFDGT
GPEVYGGWNA PIAITHSAII YCLRCMINAD MPLNQGCLAP IDIQVPSPSI LSPTKSAAVV
GGNVVTSQRI TDVVLKAFRA CAASQGCCNN LTFGTNSKRD PETGETIPGF GYYETIAGGS
GAGPTWSGES GIHVHMTNTR ITDPEILEKR YPTLLRQFTL REGSGGKGKN PGGDGVVRDI
EFLSPMEVSI LSERRVYRPY GLEGGEDAQP GMNLWVTKDV DTGVERVVNI GGKNTVSMKT
HDRIVINTAG GGGWGAVSA
//
