ID G3YGR6_ASPNA Unreviewed; 798 AA.
AC G3YGR6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Heat shock protein 78, mitochondrial {ECO:0008006|Google:ProtNLM};
GN ORFNames=ASPNIDRAFT_208225 {ECO:0000313|EMBL:EHA17969.1};
OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 /
OS NCTC 3858a / NRRL 328 / USDA 3528.7).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=380704 {ECO:0000313|EMBL:EHA17969.1, ECO:0000313|Proteomes:UP000009038};
RN [1] {ECO:0000313|EMBL:EHA17969.1, ECO:0000313|Proteomes:UP000009038}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a /
RC NRRL 328 / USDA 3528.7 {ECO:0000313|Proteomes:UP000009038};
RX PubMed=21543515; DOI=10.1101/gr.112169.110;
RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.,
RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., Albermann K.,
RA Berka R.M., Braus G.H., Braus-Stromeyer S.A., Corrochano L.M., Dai Z.,
RA van Dijck P.W., Hofmann G., Lasure L.L., Magnuson J.K., Menke H.,
RA Meijer M., Meijer S.L., Nielsen J.B., Nielsen M.L., van Ooyen A.J.,
RA Pel H.J., Poulsen L., Samson R.A., Stam H., Tsang A., van den Brink J.M.,
RA Atkins A., Aerts A., Shapiro H., Pangilinan J., Salamov A., Lou Y.,
RA Lindquist E., Lucas S., Grimwood J., Grigoriev I.V., Kubicek C.P.,
RA Martinez D., van Peij N.N., Roubos J.A., Nielsen J., Baker S.E.;
RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC 1015
RT versus enzyme-producing CBS 513.88.";
RL Genome Res. 21:885-897(2011).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|ARBA:ARBA00008675, ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA17969.1}.
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DR EMBL; ACJE01000021; EHA17969.1; -; Genomic_DNA.
DR AlphaFoldDB; G3YGR6; -.
DR STRING; 380704.G3YGR6; -.
DR VEuPathDB; FungiDB:ASPNIDRAFT2_1113616; -.
DR HOGENOM; CLU_005070_4_0_1; -.
DR Proteomes; UP000009038; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF18; HEAT SHOCK PROTEIN 78, MITOCHONDRIAL; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432}.
FT DOMAIN 116..260
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 516..709
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 694..785
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT COILED 329..409
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 798 AA; 88274 MW; 5562EB786BBFBEBD CRC64;
MSSRLQLARG RLLRPSSLPS SNRVLQPSQA LRLLARTRIA NLARHPSVLP IRTYANGRPH
PPGGTHRMNL GGEPEKSALE QFGVDLTARA KAGKLDPVIG RDAEIHRTIQ VLSRRTKNNP
VLIGAAGTGK TAVLEGLAQR IVQGDVPESI KDKRVIALDL GSLIAGAKFR GDFEERLKSV
LKEVEDAQGG VILFIDELHT LLGLGKAEGS IDASNLLKPA LSRGELQCCG ATTLNEYRLI
EKDVALARRF QPIQVGEPSV AATISILRGI KNKYEVHHGV RITDGALVAA ATYSNRYITD
RFLPDKAIDL VDEAASALRL QQESKPDVIR ELDRDITTIQ IELESLRKET DVSSRERRDK
LQEDLKVKQE EARKLTEVWE KEKAEIEELK RAKEELERAR FELEKAQREG NFAKAGELRY
ATIPSLEAKL PKEGEEQATK AQTSLIHDSV TADDIGNVVS RTTGIPVNKL MAGEVEKLIK
MEDTLRKSVR GQDEALSAVA NAVRMQRAGL SGENRPLASF MFLGPTGVGK TELCKKMAEF
LFSTETAVVR FDMSEFQEKH TISRLIGSPA GYVGYDDAGQ LTEAVRRKPY AVLLFDEFEK
AHRDISALLL QVLDEGFLTD SQGHKVDFRN TLIVLTSNLG ADILVGADPL HPYKEGGDNE
LSPETKKSVM DVVQSAYPPE FLNRIDEFII FKRLSRDALR DIVDIRVKEL QSRLDDRRMT
LQVDDEIKDW LCDKGYDPKY GARPLNRLIA KEIGNKLADK IIRGEVTSGQ TARVTFNADK
SGLAVAAEAP VATETESS
//
