ID G4CF67_9NEIS Unreviewed; 820 AA.
AC G4CF67;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 61.
DE SubName: Full=Copper-exporting ATPase {ECO:0000313|EMBL:EGY53511.1};
DE EC=3.6.3.4 {ECO:0000313|EMBL:EGY53511.1};
GN ORFNames=HMPREF9371_0256 {ECO:0000313|EMBL:EGY53511.1};
OS Neisseria shayeganii 871.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1032488 {ECO:0000313|EMBL:EGY53511.1, ECO:0000313|Proteomes:UP000003019};
RN [1] {ECO:0000313|EMBL:EGY53511.1, ECO:0000313|Proteomes:UP000003019}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=871 {ECO:0000313|EMBL:EGY53511.1,
RC ECO:0000313|Proteomes:UP000003019};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|ARBA:ARBA00006024,
CC ECO:0000256|RuleBase:RU362081}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY53511.1}.
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DR EMBL; AGAY01000008; EGY53511.1; -; Genomic_DNA.
DR RefSeq; WP_009117950.1; NZ_JH164926.1.
DR AlphaFoldDB; G4CF67; -.
DR STRING; 1032488.HMPREF9371_0256; -.
DR PATRIC; fig|1032488.3.peg.240; -.
DR HOGENOM; CLU_001771_0_3_4; -.
DR OrthoDB; 8552908at2; -.
DR Proteomes; UP000003019; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015662; F:P-type ion transporter activity; IEA:UniProt.
DR CDD; cd00371; HMA; 1.
DR CDD; cd02079; P-type_ATPase_HM; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR021993; ATPase-cat-bd.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF5; CATION-TRANSPORTING P-TYPE ATPASE-RELATED; 1.
DR Pfam; PF12156; ATPase-cat_bd; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00943; CUATPASE.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Cell membrane {ECO:0000256|RuleBase:RU362081};
KW Hydrolase {ECO:0000313|EMBL:EGY53511.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000003019};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 187..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 214..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 257..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 280..298
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 437..458
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 464..488
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 775..794
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 99..165
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 820 AA; 88583 MW; EE8B3B25FFD3C1B3 CRC64;
MKNQTEHASP TCFHCGLDVP ASVDLPVVFE GETHSTCCVG CQAVAESIIA AGLGSYYHRR
TADAERAALP PPDVLEQLKL YDLPDVQAEF VETRSEHERE AVLMLGGVTC AACVWLIEQQ
LLRLDGVLRA EVNYSTLRAR VAWDNSRVAL SDILLCVRRT GYEAAPYDAN KLEVQAQAER
RQALTRLWVA GLAMMQVMMY IIPVYLYGGE IEPWFLWILH WANMILTLPV MFYSAVPFFK
GAWRDMKNRR LGMDTPVALA ISAAFGASFV ALVLGYERGI YFDSVSMFVF LLLGGRYLEQ
MARRKAGDAA ERLVKLVPAF CHRLPAYPDT AQMEEAVVAR LQSGEVVLVK AGEVVPVDGE
VLSGESEVNE AILTGESLPV AKYAGSAVTA GTLNIGSPLV VRVSETGSGT RLGHIVRLLD
RALAEKPRMV ELADRHASSF VLGLLLLSAV VFGVWLYLAD FETAWWITVS LLVVTCPCAL
SLATPAALAA STGRLAGEGV LIGRGHSLET LAKVDTVVLD KTGTLTEGRL AVENILLADG
VSREQAVAVA QALERQSEHP VAQALMALPA AGVSGSLQPR QTLNRVGHGM AAVFDGDGQE
EWRIGRFSYV AEIAGRLPES LHTEHAGTAV YLGHRRGFAA VFLLQDQIKN GVADMVAALH
AQGLRLHLLS GDREAAVQSV ARRLGLDALR AEAAPEDKLA YVQDLQAQGR CVLMVGDGIN
DAPVLAQADV SLAVAEGADV AREGADVLLI NSDMRILPQL TAAARRTRRI IRENLWWATA
YNLIAVPLAA FGYVTPFVAA LGMSLSSLLV SANALRLLRK
//
