ID G4CMD4_9NEIS Unreviewed; 503 AA.
AC G4CMD4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=AGSC family alanine:sodium (Na+) symporter {ECO:0000313|EMBL:EGZ51214.1};
GN ORFNames=HMPREF9370_0243 {ECO:0000313|EMBL:EGZ51214.1};
OS Neisseria wadsworthii 9715.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1030841 {ECO:0000313|EMBL:EGZ51214.1, ECO:0000313|Proteomes:UP000005336};
RN [1] {ECO:0000313|EMBL:EGZ51214.1, ECO:0000313|Proteomes:UP000005336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9715 {ECO:0000313|EMBL:EGZ51214.1,
RC ECO:0000313|Proteomes:UP000005336};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|RuleBase:RU363064}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGZ51214.1}.
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DR EMBL; AGAZ01000008; EGZ51214.1; -; Genomic_DNA.
DR AlphaFoldDB; G4CMD4; -.
DR STRING; 1030841.HMPREF9370_0243; -.
DR PATRIC; fig|1030841.3.peg.251; -.
DR HOGENOM; CLU_024867_0_1_4; -.
DR Proteomes; UP000005336; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|RuleBase:RU363064};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 35..60
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 217..237
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 417..442
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 448..471
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 503 AA; 54000 MW; CA8E46C7D26B9F92 CRC64;
MDKFKECLDQ GQHGVYALDL MHCGVNAGND FVWTWLVFIL VAVGLFFTLA TGFVQVRLLA
RSIKEMLGSR SEGDDSHGHG ITPFQAFATG LASRVGTGNI AGVAIAISLG GPGAVLWMWL
TALLGMSSAF AESSLAQLFK IRDHGNNQFR GGPAYYITRG MGQKWLGILF ALSLILCFGF
VFNAIQANTI IESVKSASGC ASGSGDCETA WHSYKHILGV GLVILTAPII FGGIRRVSRI
AEALVPLMAS AYLLVAIFIV ATNISEVPGM FSMIINSAFN FESAAGGFTG SAIAAAMQQG
IKRGLFSNEA GMGSAPNAAA AADVKHPVSQ GMIQMLGVFV DTIIVCSCTA FVILLSDVPN
AANLTGSQLT QAALESQIGV FGQYFLAVVL FMFCYSSIIG NYAYAESNVQ FIKNGRLTLA
LFRMAVLAFV YFGSVVKVGL VWDMGDLSMG IMAFINLIAI MILSPLVFML LRDYQRKLRM
GKEPVFKLSE HPTLKRKIKS DIW
//
