ID G4CNL5_9NEIS Unreviewed; 386 AA.
AC G4CNL5;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Putative 8-amino-7-oxononanoate synthase {ECO:0000256|ARBA:ARBA00021531};
GN Name=metC {ECO:0000313|EMBL:EGZ49363.1};
GN ORFNames=HMPREF9370_0674 {ECO:0000313|EMBL:EGZ49363.1};
OS Neisseria wadsworthii 9715.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1030841 {ECO:0000313|EMBL:EGZ49363.1, ECO:0000313|Proteomes:UP000005336};
RN [1] {ECO:0000313|EMBL:EGZ49363.1, ECO:0000313|Proteomes:UP000005336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=9715 {ECO:0000313|EMBL:EGZ49363.1,
RC ECO:0000313|Proteomes:UP000005336};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGZ49363.1}.
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DR EMBL; AGAZ01000028; EGZ49363.1; -; Genomic_DNA.
DR RefSeq; WP_009115820.1; NZ_JH165159.1.
DR AlphaFoldDB; G4CNL5; -.
DR STRING; 1030841.HMPREF9370_0674; -.
DR PATRIC; fig|1030841.3.peg.666; -.
DR HOGENOM; CLU_018986_2_0_4; -.
DR OrthoDB; 9805807at2; -.
DR Proteomes; UP000005336; Unassembled WGS sequence.
DR GO; GO:0004121; F:cystathionine beta-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR11808:SF92; CYSTATHIONINE GAMMA-SYNTHASE; 1.
DR PANTHER; PTHR11808; TRANS-SULFURATION ENZYME FAMILY MEMBER; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:EGZ49363.1};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2}.
FT MOD_RES 199
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 386 AA; 41981 MW; 1DA9B126D7CCE350 CRC64;
MPYQFSTEAI HTGYDCDEHN RAIMPPIYQN SMFAMHEIGE KIPYRYSRLA NPTRKVLEDT
VAALEHGSHG FAFASGMAGI DCVFRTFLAP GDTIVAVGDI YGGSYDLLTQ VYAKWGVNVV
FADLTQPENL DRILAEGKVK LVWLETPSNP LLRLVDIPLL AAKAKAAGAL VGIDNTFATP
YLQNPLDMGC DIVFHSATKY LCGHSDVLMG VVVAKTPELA EPLQSMMVNT GGVAGPMDCA
LVLRGIKTLA LRMQQHCNNA LELARRLEQH PAVEKVFYPG LPNHEHHKLA GQQMRGFGGV
VSVYLKNDSV SAADSVVKNM KLVKMASSLG GVESLVNHSY SQSHSGMPPE LKQELGIRKG
LLRFSVGIED IDDIYQDIAA ALDTVA
//
