ID G4CZR8_9ACTN Unreviewed; 227 AA.
AC G4CZR8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=LexA repressor {ECO:0000313|EMBL:EGY76987.1};
DE EC=3.4.21.88 {ECO:0000313|EMBL:EGY76987.1};
GN ORFNames=HMPREF9153_1940 {ECO:0000313|EMBL:EGY76987.1};
OS Cutibacterium avidum ATCC 25577.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Cutibacterium.
OX NCBI_TaxID=997355 {ECO:0000313|EMBL:EGY76987.1, ECO:0000313|Proteomes:UP000005332};
RN [1] {ECO:0000313|EMBL:EGY76987.1, ECO:0000313|Proteomes:UP000005332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25577 {ECO:0000313|EMBL:EGY76987.1,
RC ECO:0000313|Proteomes:UP000005332};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY76987.1}.
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DR EMBL; AGBA01000015; EGY76987.1; -; Genomic_DNA.
DR RefSeq; WP_004811560.1; NZ_JH165054.1.
DR AlphaFoldDB; G4CZR8; -.
DR PATRIC; fig|997355.3.peg.1909; -.
DR HOGENOM; CLU_1234126_0_0_11; -.
DR Proteomes; UP000005332; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd06529; S24_LexA-like; 1.
DR Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR039418; LexA-like.
DR InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR InterPro; IPR006199; LexA_DNA-bd_dom.
DR InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR33516; LEXA REPRESSOR; 1.
DR PANTHER; PTHR33516:SF2; LEXA REPRESSOR; 1.
DR Pfam; PF01726; LexA_DNA_bind; 1.
DR Pfam; PF00717; Peptidase_S24; 1.
DR SUPFAM; SSF51306; LexA/Signal peptidase; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Hydrolase {ECO:0000313|EMBL:EGY76987.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005332};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 32..86
FT /note="LexA repressor DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF01726"
FT DOMAIN 115..221
FT /note="Peptidase S24/S26A/S26B/S26C"
FT /evidence="ECO:0000259|Pfam:PF00717"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 227 AA; 24091 MW; ADD33E89467C6876 CRC64;
MTTDTPGTDS SDSAAVSSAV PFTTTRQPSA KEHAVLTAVK EGLRRDGRAP TVRALADMTG
AASTSTVQRR ISALIDLGLL RRTDGTLEVV EDVVDVNDPH GPQAFQIEVF NPNEIADDEH
HDTVIAVPSQ LLSHGDHVVV VVRDDGMAPD FHVGDLVLVQ QLPVADLPDD PPETYFVAAT
VGGTTIIRSL AKLGGKPWLM ASNPAHSPVN LDDASLIGRA VSIMRRL
//
