ID G4D0G9_9ACTN Unreviewed; 356 AA.
AC G4D0G9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Glucokinase {ECO:0000256|ARBA:ARBA00014701};
DE EC=2.7.1.2 {ECO:0000256|ARBA:ARBA00012323};
DE AltName: Full=Glucose kinase {ECO:0000256|ARBA:ARBA00032386};
GN Name=glk {ECO:0000313|EMBL:EGY77238.1};
GN ORFNames=HMPREF9153_2191 {ECO:0000313|EMBL:EGY77238.1};
OS Cutibacterium avidum ATCC 25577.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Propionibacteriaceae; Cutibacterium.
OX NCBI_TaxID=997355 {ECO:0000313|EMBL:EGY77238.1, ECO:0000313|Proteomes:UP000005332};
RN [1] {ECO:0000313|EMBL:EGY77238.1, ECO:0000313|Proteomes:UP000005332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25577 {ECO:0000313|EMBL:EGY77238.1,
RC ECO:0000313|Proteomes:UP000005332};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ROK (NagC/XylR) family.
CC {ECO:0000256|ARBA:ARBA00006479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGY77238.1}.
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DR EMBL; AGBA01000015; EGY77238.1; -; Genomic_DNA.
DR RefSeq; WP_004811845.1; NZ_JH165054.1.
DR AlphaFoldDB; G4D0G9; -.
DR GeneID; 29843625; -.
DR PATRIC; fig|997355.3.peg.2166; -.
DR HOGENOM; CLU_036604_0_0_11; -.
DR Proteomes; UP000005332; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004340; F:glucokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006096; P:glycolytic process; IEA:InterPro.
DR CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000600; ROK.
DR InterPro; IPR004654; ROK_glcA.
DR NCBIfam; TIGR00744; ROK_glcA_fam; 1.
DR PANTHER; PTHR18964:SF149; BIFUNCTIONAL UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE_N-ACETYLMANNOSAMINE KINASE; 1.
DR PANTHER; PTHR18964; ROK (REPRESSOR, ORF, KINASE) FAMILY; 1.
DR Pfam; PF00480; ROK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
DR PROSITE; PS01125; ROK; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152};
KW Kinase {ECO:0000313|EMBL:EGY77238.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005332};
KW Transferase {ECO:0000313|EMBL:EGY77238.1}.
SQ SEQUENCE 356 AA; 38024 MW; DC4577194004F88D CRC64;
MLSVGIDIGG TKVAAGVVDE NGQIVQRIQC PTPSRSPEAV EDAIVESVRE LSHDLPICAV
GIGAAGWIDT EQALVRFSPH LAWRNEPLRD RLSERITVPV LVDNDANAAA WAEFRFGAGK
GSRVMVCLTL GTGIGGALVI NGRMFRGRYG MAGEFGHMTV VPDGHWCPCG NRGCWEQYAS
GNSLVRDARA LLAEGAPGVQ DLLSYVTDRD PDNLVGPDVT RAAVDGDRLA IELIADIGIW
LGRGMANLAA ALDPDLFVVG GGVSAAGDLL LEPARTVYAR TLTGRGFRPM ADIQKAHFGN
DAGLIGAADL ARHSINEPPG LARGFWPRRR TAVRKPRRTL RQSLTETLTG PVVRDR
//
