ID G4F6W8_9GAMM Unreviewed; 378 AA.
AC G4F6W8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=4-hydroxybutyrate dehydrogenase {ECO:0000313|EMBL:EHA15716.1};
GN ORFNames=HAL1_10667 {ECO:0000313|EMBL:EHA15716.1};
OS Halomonas sp. HAL1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=550984 {ECO:0000313|EMBL:EHA15716.1, ECO:0000313|Proteomes:UP000005692};
RN [1] {ECO:0000313|EMBL:EHA15716.1, ECO:0000313|Proteomes:UP000005692}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain {ECO:0000313|Proteomes:UP000005692};
RX PubMed=22156396; DOI=10.1128/JB.06359-11;
RA Lin Y., Fan H., Hao X., Johnstone L., Hu Y., Wei G., Alwathnani H.A.,
RA Wang G., Rensing C.;
RT "Draft Genome Sequence of Halomonas sp. Strain HAL1, a Moderately
RT Halophilic Arsenite-Oxidizing Bacterium Isolated from Gold-Mine Soil.";
RL J. Bacteriol. 194:199-200(2012).
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA15716.1}.
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DR EMBL; AGIB01000045; EHA15716.1; -; Genomic_DNA.
DR RefSeq; WP_008958032.1; NZ_CP130610.1.
DR AlphaFoldDB; G4F6W8; -.
DR PATRIC; fig|550984.5.peg.2076; -.
DR Proteomes; UP000005692; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd14861; Fe-ADH-like; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 1.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR PROSITE; PS00913; ADH_IRON_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 8..369
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 378 AA; 40288 MW; E658B55B7C8D2386 CRC64;
MALINYVTQI QFDFGAASLL QQECDRLGIR HPMVVTDAGV RAAGIVDQVL KHLRDPNPAI
YDQTPPNPNE AAVREAVAQY REGGFDGLIA IGGGSSIDLA KGVAICGTHE GSLKSFAVVE
GGSERITAAT APVIAIPTTA GTGSEVGRGA ILILEDGRKV GLLSPHLVPK SAICDPELTL
SLPAQMTAAT GMDALSHCLE TFMSAAFNPP ADGIALDGLR RGWLNIERAT RHPGDREARM
NMMSASMQGA MAFQKGLGCV HSLSHSLGGI NPRLHHGTLN AIFLPAVIEF NSSCESVKHE
QKLERIAQTM QLNSPADIGP AIKDMSKRLD LPMGLAELDV SEALFPRIIK GALADHTHKT
NPRVASEQDY QWMLEQSL
//
