ID G4F9W0_9GAMM Unreviewed; 488 AA.
AC G4F9W0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Na+/H+ antiporter {ECO:0000313|EMBL:EHA14474.1};
GN ORFNames=HAL1_15961 {ECO:0000313|EMBL:EHA14474.1};
OS Halomonas sp. HAL1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Halomonadaceae; Halomonas.
OX NCBI_TaxID=550984 {ECO:0000313|EMBL:EHA14474.1, ECO:0000313|Proteomes:UP000005692};
RN [1] {ECO:0000313|EMBL:EHA14474.1, ECO:0000313|Proteomes:UP000005692}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain {ECO:0000313|Proteomes:UP000005692};
RX PubMed=22156396; DOI=10.1128/JB.06359-11;
RA Lin Y., Fan H., Hao X., Johnstone L., Hu Y., Wei G., Alwathnani H.A.,
RA Wang G., Rensing C.;
RT "Draft Genome Sequence of Halomonas sp. Strain HAL1, a Moderately
RT Halophilic Arsenite-Oxidizing Bacterium Isolated from Gold-Mine Soil.";
RL J. Bacteriol. 194:199-200(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter
CC family. {ECO:0000256|ARBA:ARBA00025753}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EHA14474.1}.
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DR EMBL; AGIB01000080; EHA14474.1; -; Genomic_DNA.
DR RefSeq; WP_008959063.1; NZ_CP130610.1.
DR AlphaFoldDB; G4F9W0; -.
DR PATRIC; fig|550984.5.peg.3080; -.
DR Proteomes; UP000005692; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR InterPro; IPR045016; NhaD-like.
DR NCBIfam; NF038006; NhaD_1; 1.
DR PANTHER; PTHR43269; SODIUM/PROTON ANTIPORTER 1-RELATED; 1.
DR PANTHER; PTHR43269:SF2; SODIUM_PROTON ANTIPORTER 1-RELATED; 1.
DR Pfam; PF03600; CitMHS; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 44..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 228..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..312
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 463..483
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 58..433
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 488 AA; 53885 MW; 7B3D496700708AD5 CRC64;
MKPPNVLATR HYASRVAWLL LACSLFIFPS LSYAAAGPLD LTLTLTGISS VVIFVLAYAL
VMTEELLHMR KSKPVLVAAG LIWALVAWVY VQAGMPEEAQ TAFRETLLEY AELLLFLLVA
MTYINAMEER RVFDALRSWL VRKGFSYRSL FWITGVMAFG ISAIANNMTT AMLMCAVVLK
VAEGDKKFIG LCCVNVVVAS NAGGAFSPFG DITTLMVWQA GQVPFEGFFA LLVPAVVNFM
VPAVIMNFFI ANRQPAALQE NVWLKRGARR IIVLFLITVA ISVLCHSILY LPPAMGMMFG
LGLLQFFGYY LRRSLPRSLE RKRERYSRRG DWKKLEQLGS VVPFDIFSRI ARSEWDTLLF
FYGVVMCVGG LGFMGYLSLL SETLYGNWNP VWANVVLGLI SAVVDNIPVM FAVLSMAPDM
SEGNWLLVTL TAGVGGSLLS MGSAAGVALM GQARGIYTFA VHLRWMPAIL LGYAASIVTH
LWINASMF
//
