ID G4HJA8_9BACL Unreviewed; 914 AA.
AC G4HJA8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=PaelaDRAFT_4069 {ECO:0000313|EMBL:EHB62826.1};
OS Paenibacillus lactis 154.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=743719 {ECO:0000313|EMBL:EHB62826.1, ECO:0000313|Proteomes:UP000003891};
RN [1] {ECO:0000313|EMBL:EHB62826.1, ECO:0000313|Proteomes:UP000003891}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=154 {ECO:0000313|EMBL:EHB62826.1,
RC ECO:0000313|Proteomes:UP000003891};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Siebers A., Thelen M., Hugenholtz P.,
RA Allgaier M., Woyke T.J.;
RT "The draft genome of Paenibacillus lactis 154.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
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DR EMBL; AGIP01000009; EHB62826.1; -; Genomic_DNA.
DR RefSeq; WP_007131232.1; NZ_AGIP01000009.1.
DR AlphaFoldDB; G4HJA8; -.
DR STRING; 743719.PaelaDRAFT_4069; -.
DR PATRIC; fig|743719.3.peg.4121; -.
DR eggNOG; COG0265; Bacteria.
DR eggNOG; COG2010; Bacteria.
DR eggNOG; COG4409; Bacteria.
DR OrthoDB; 7294637at2; -.
DR Proteomes; UP000003891; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.30.1920.20; -; 1.
DR InterPro; IPR025883; Cadherin-like_b_sandwich.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR Pfam; PF12733; Cadherin-like; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR SMART; SM00560; LamGL; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..914
FT /note="exo-alpha-sialidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5038957437"
FT DOMAIN 555..697
FT /note="LamG-like jellyroll fold"
FT /evidence="ECO:0000259|SMART:SM00560"
SQ SEQUENCE 914 AA; 100062 MW; 5110FDBFD9B02421 CRC64;
MMRPLRKAFI GWMVFIVMAA CFPHGPVSLS NAAKAETAAD GEAQFRNIDL FVAGTEGYHT
FRIPTVLTTM DGTLLAFAEG RKNSASDTGD IDLVLKRSMD GGTTWGSLQT VCDMGTDTCG
NPTAVQDESN GRIWLFMNHN YGEDTIEEIN NGTSRGVRTI WSAYSDDDGA SWSEPVNRFE
EVQPPDIRWD ATGPAIGIQL RHGPNQGRLV IPAIGRNIQS DDHGLTWYQS GYIQGDTNEA
TVVELTDGTL MRNDRLSANK ERKRRAISTS RDQGATWSPV YYAPELIDPV VQASIVRYLP
ADNDLGSRLL VFANPASENV RENMTVRLSH DDGATWPVAK TVYSGHSAYS SLTVLPDGTI
GLLFEGGGYT PYDKIMFATF NLAWFETEDV QLDGLVFSEG SLSPVFRSDI EHYRLTLYEG
SEAVTVTPIA SKAGVEIEIA GEPAAPGIPR TIRLGELDKL LVTARLGHRT RTYTIELDRS
RPRPELLLHW DFEQVSVGGV TDVTGRGHTG LLKNGAAILP GAVRSDGQGH VLHLDAMQRS
HVEITKADDL HFGTGDFTFA TWVNPETLSR QRHLLIWYGT AGRGVPQWWM SVEQNGAVRM
NLNGLPLNRE IGTATPSGLV KTGEWAHVAG VRQGGNLLVY VNGELAATSA QFDGAAMNVT
NEDAPPLVGF DKGTVANRDW SGSLDDVRIY RHALDPSDIR KLYQLPFDAA APVTEAVVTP
NEPDGMNGWY TSDVTVELTA ADQGSKVTYT EYRLNGGEWT NYSGAVSVSA EGITTMEYRS
RDGAGNVEET RTLVLPIDKT EPELTVTPNL EVLWPPNRKW VPMEIRLDPK DESSGIDSIA
LVSVTTEGTP DPLEGIRDAD IGTADTSFQL LAANHRRGEK RVYIITYEAR DKAGHSTTKT
ITVEVARTVK EDER
//
