ID G4HPP0_9BACL Unreviewed; 436 AA.
AC G4HPP0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Nucleotide sugar dehydrogenase {ECO:0000313|EMBL:EHB47577.1};
GN ORFNames=PaelaDRAFT_5951 {ECO:0000313|EMBL:EHB47577.1};
OS Paenibacillus lactis 154.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=743719 {ECO:0000313|EMBL:EHB47577.1, ECO:0000313|Proteomes:UP000003891};
RN [1] {ECO:0000313|EMBL:EHB47577.1, ECO:0000313|Proteomes:UP000003891}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=154 {ECO:0000313|EMBL:EHB47577.1,
RC ECO:0000313|Proteomes:UP000003891};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Peters L., Land M.L., Hauser L., Siebers A., Thelen M., Hugenholtz P.,
RA Allgaier M., Woyke T.J.;
RT "The draft genome of Paenibacillus lactis 154.";
RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
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DR EMBL; AGIP01000027; EHB47577.1; -; Genomic_DNA.
DR RefSeq; WP_007133098.1; NZ_AGIP01000027.1.
DR AlphaFoldDB; G4HPP0; -.
DR STRING; 743719.PaelaDRAFT_5951; -.
DR PATRIC; fig|743719.3.peg.6049; -.
DR eggNOG; COG0677; Bacteria.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000003891; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 321..423
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 436 AA; 48009 MW; 8298992301282560 CRC64;
MEIYQKIADR VDKLAVVGLG YVGLPLAVAF AKKVDVIGFD LNSEKVMQYR NGIDATGELE
LELAGCTAEF TSDPDKLKEA RCFIVAVPTP VKSGNVPDLK FVRDASRLIG RVLAPGSIVV
YESTVYPGVT EDVCIPILEE ESGLAFGTDF KVGYSPERIN PGDRVHRLEN IVKIVSGSDP
EALETVARLY ELIIEAGVHR AESIKVAEAA KVIENAQRDI NIAFMNELSM LFNEMDIDTN
AVLRAAGTKW NFLPFRPGLV GGHCIGIDPY YLTYKAEDTG YHSKIILAGR HINDGMGKYI
AQQVIKLAVQ KGLDISHAKV AVLGLTFKED CRDIRNSKVI DIIRELQDYG VQPLVVDPCA
DGKQAYKEYG IELTALEELQ DIQVAIVAVA HSEFKQLGIT EYTGMFGSGQ ANIMIDVKGI
YPRSLFENNG FHYWSL
//
