ID G4LWP8_SCHMA Unreviewed; 253 AA.
AC G4LWP8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=ribose-5-phosphate isomerase {ECO:0000256|ARBA:ARBA00011959};
DE EC=5.3.1.6 {ECO:0000256|ARBA:ARBA00011959};
DE AltName: Full=Phosphoriboisomerase {ECO:0000256|ARBA:ARBA00029734};
OS Schistosoma mansoni (Blood fluke).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_148770.1};
RN [1] {ECO:0000313|Proteomes:UP000008854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA Zerlotini A., Dunne D.W., Berriman M.;
RT "A systematically improved high quality genome and transcriptome of the
RT human blood fluke Schistosoma mansoni.";
RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN [2] {ECO:0000313|WBParaSite:Smp_148770.1}
RP IDENTIFICATION.
RC STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_148770.1};
RG WormBaseParasite;
RL Submitted (DEC-2018) to UniProtKB.
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribose
CC 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step
CC 1/1. {ECO:0000256|ARBA:ARBA00004988}.
CC -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
CC {ECO:0000256|ARBA:ARBA00008088}.
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DR RefSeq; XP_018645688.1; XM_018791175.1.
DR AlphaFoldDB; G4LWP8; -.
DR STRING; 6183.G4LWP8; -.
DR EnsemblMetazoa; Smp_148770.1; Smp_148770.1; Smp_148770.
DR GeneID; 8341523; -.
DR KEGG; smm:Smp_148770; -.
DR WBParaSite; Smp_148770.1; Smp_148770.1; Smp_148770.
DR CTD; 8341523; -.
DR eggNOG; KOG3075; Eukaryota.
DR HOGENOM; CLU_056590_0_2_1; -.
DR InParanoid; G4LWP8; -.
DR OrthoDB; 5232260at2759; -.
DR PhylomeDB; G4LWP8; -.
DR UniPathway; UPA00115; UER00412.
DR Proteomes; UP000008854; Unassembled WGS sequence.
DR GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:InterPro.
DR CDD; cd01398; RPI_A; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1360; -; 1.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR004788; Ribose5P_isomerase_type_A.
DR NCBIfam; TIGR00021; rpiA; 1.
DR PANTHER; PTHR11934; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11934:SF0; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF06026; Rib_5-P_isom_A; 1.
DR SUPFAM; SSF75445; D-ribose-5-phosphate isomerase (RpiA), lid domain; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008854}.
SQ SEQUENCE 253 AA; 28232 MW; 40422833A23320DB CRC64;
MINSDALESA KQIACHSAIS DWLEDNQIIG LGSGTTIKYA VEYIAEKVKK ENLQIQCIPT
SFQARQLLIN HKLPVTELDI CEQIDVTFDG ADEVDEHLHL IKGGGGCLLQ EKIVASCTND
FIAIIDERKH SKRLGSYWTK GLPIEVVPMA FKPVQTRIQK LFGGQAILRE AVSKMGPVVT
DNGNFLLDWK FDTNKQYYWP DVNVQLSQIP GIVDTGLFIN MTSRIYIGNL NGTVTKLEGK
SSNQHKLNNM NNL
//
