ID   G4MA77_9BURK            Unreviewed;       336 AA.
AC   G4MA77;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   SubName: Full=Ca2+/Na+ antiporter {ECO:0000313|EMBL:CCD38056.1};
GN   ORFNames=BKIR_c23_2154 {ECO:0000313|EMBL:CCD38056.1};
OS   Candidatus Paraburkholderia kirkii UZHbot1.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=1055526 {ECO:0000313|EMBL:CCD38056.1, ECO:0000313|Proteomes:UP000003511};
RN   [1] {ECO:0000313|EMBL:CCD38056.1, ECO:0000313|Proteomes:UP000003511}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UZHbot1 {ECO:0000313|EMBL:CCD38056.1,
RC   ECO:0000313|Proteomes:UP000003511};
RA   Carlier A.;
RL   Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CCD38056.1, ECO:0000313|Proteomes:UP000003511}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UZHbot1 {ECO:0000313|EMBL:CCD38056.1,
RC   ECO:0000313|Proteomes:UP000003511};
RA   Carlier A.L., Eberl L.;
RT   "Draft genome sequence of Candidatus Burkholderia kirkii.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCD38056.1}.
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DR   EMBL; CAFE01000151; CCD38056.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4MA77; -.
DR   STRING; 1055526.BKIR_c23_2154; -.
DR   HOGENOM; CLU_072251_0_0_4; -.
DR   BioCyc; CBUR1055526:G10QW-145-MONOMER; -.
DR   Proteomes; UP000003511; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   InterPro; IPR004481; K/Na/Ca-exchanger.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   PANTHER; PTHR10846:SF8; INNER MEMBRANE PROTEIN YRBG; 1.
DR   PANTHER; PTHR10846; SODIUM/POTASSIUM/CALCIUM EXCHANGER; 1.
DR   Pfam; PF01699; Na_Ca_ex; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000003511};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        43..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        74..99
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        144..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        259..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        313..332
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          5..160
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
FT   DOMAIN          196..333
FT                   /note="Sodium/calcium exchanger membrane region"
FT                   /evidence="ECO:0000259|Pfam:PF01699"
SQ   SEQUENCE   336 AA;  35382 MW;  D9BBA6B0DE5B9BE1 CRC64;
     MTMLFVELAL MLAVILIASE LFTNALEHLG ERLGISEGVT GSLFAAVGTA LPETTVPIIA
     LLGGTPSRAV NEEIGVGAIL GAPLMLATLS TCLMTVAILK SRGLRGRIMP EHSGFTRDLN
     FFLFAFLIAC AAMFVPHHAW QIRALFAVGL VALYVIYVVS TFRASAKLVE GGHGTEAPEA
     LFASRLGLKT SLGTIMLQFF VGIVLLVGGA KGFIHGVEGV SHALGISALL LSLIIIPIAT
     ELPEKVNSIL WARRGKDTLA FGNITGAMVF QGTLLPAIGI MLTPWEPRVE VLTGVLITLA
     ASAWLRINAN GSGVALWALL GNGVLYAAYL VLTLGR
//