GenomeNet

Database: UniProt
Entry: G4NA54
LinkDB: G4NA54
Original site: G4NA54 
ID   XYN4_MAGO7              Reviewed;         231 AA.
AC   G4NA54;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 1.
DT   16-JAN-2019, entry version 33.
DE   RecName: Full=Endo-1,4-beta-xylanase 4;
DE            Short=Xylanase 4;
DE            EC=3.2.1.8;
DE   AltName: Full=1,4-beta-D-xylan xylanohydrolase 4;
DE   Flags: Precursor;
GN   Name=XYL4; ORFNames=MGG_08424;
OS   Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice
OS   blast fungus) (Pyricularia oryzae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Magnaporthales; Magnaporthaceae;
OC   Magnaporthe.
OX   NCBI_TaxID=242507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958;
RX   PubMed=15846337; DOI=10.1038/nature03449;
RA   Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K.,
RA   Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D.,
RA   Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S.,
RA   Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W.,
RA   Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J.,
RA   Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "The genome sequence of the rice blast fungus Magnaporthe grisea.";
RL   Nature 434:980-986(2005).
CC   -!- FUNCTION: Endo-1,4-beta-xylanase involved in the hydrolysis of
CC       xylan, a major structural heterogeneous polysaccharide found in
CC       plant biomass representing the second most abundant polysaccharide
CC       in the biosphere, after cellulose. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Endohydrolysis of (1->4)-beta-D-xylosidic linkages in
CC         xylans.; EC=3.2.1.8;
CC   -!- PATHWAY: Glycan degradation; xylan degradation.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 11 (cellulase G)
CC       family. {ECO:0000305}.
DR   EMBL; CM001234; EHA49604.1; -; Genomic_DNA.
DR   RefSeq; XP_003715923.1; XM_003715875.1.
DR   ProteinModelPortal; G4NA54; -.
DR   SMR; G4NA54; -.
DR   STRING; 318829.MGG_08424T0; -.
DR   CAZy; GH11; Glycoside Hydrolase Family 11.
DR   EnsemblFungi; MGG_08424T0; MGG_08424T0; MGG_08424.
DR   GeneID; 2678666; -.
DR   KEGG; mgr:MGG_08424; -.
DR   EuPathDB; FungiDB:MGG_08424; -.
DR   InParanoid; G4NA54; -.
DR   KO; K01181; -.
DR   OMA; GAFSAQW; -.
DR   OrthoDB; 1306131at2759; -.
DR   UniPathway; UPA00114; -.
DR   Proteomes; UP000009058; Chromosome 4.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0031176; F:endo-1,4-beta-xylanase activity; IEA:UniProtKB-EC.
DR   GO; GO:0045493; P:xylan catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.60.120.180; -; 1.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR013319; GH11/12.
DR   InterPro; IPR018208; GH11_AS_1.
DR   InterPro; IPR033119; GH11_AS_2.
DR   InterPro; IPR033123; GH11_dom.
DR   InterPro; IPR001137; Glyco_hydro_11.
DR   Pfam; PF00457; Glyco_hydro_11; 1.
DR   PRINTS; PR00911; GLHYDRLASE11.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS00776; GH11_1; 1.
DR   PROSITE; PS00777; GH11_2; 1.
DR   PROSITE; PS51761; GH11_3; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Glycoprotein; Glycosidase;
KW   Hydrolase; Polysaccharide degradation; Reference proteome; Secreted;
KW   Signal; Xylan degradation.
FT   SIGNAL        1     18       {ECO:0000255}.
FT   CHAIN        19    231       Endo-1,4-beta-xylanase 4.
FT                                /FTId=PRO_0000429623.
FT   DOMAIN       42    230       GH11. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01097}.
FT   ACT_SITE    126    126       Nucleophile. {ECO:0000255|PROSITE-
FT                                ProRule:PRU10062}.
FT   ACT_SITE    217    217       Proton donor. {ECO:0000255|PROSITE-
FT                                ProRule:PRU10063}.
FT   CARBOHYD     99     99       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   231 AA;  25305 MW;  CECF024A9D5A795B CRC64;
     MVSFTTILVA ATAALVAANP VPPSIDEMRE IYVKSRDLHA RGGTPSSTGT HDGFYYSWWT
     DNGAQATYTN NAGGSYSITW SGNGNLVGGK GWNPGSARNV TYSANYRPNG NSYLSVYGWT
     RNPLVEYYVV ENFGTYDPSS QASRKGTINV DGATYQVAQS TRTNQPSIDG TRTFQQYWSV
     RQQKRSSGTV DMKKHFDAWA SMGMKLGTHD YQIVATEGYF SSGSSTVTIQ R
//
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