ID   G4QJ85_GLANF            Unreviewed;       726 AA.
AC   G4QJ85;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE            EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN   OrderedLocusNames=GNIT_0809 {ECO:0000313|EMBL:AEP28953.1};
OS   Glaciecola nitratireducens (strain JCM 12485 / KCTC 12276 / FR1064).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Glaciecola.
OX   NCBI_TaxID=1085623 {ECO:0000313|EMBL:AEP28953.1, ECO:0000313|Proteomes:UP000009282};
RN   [1] {ECO:0000313|EMBL:AEP28953.1, ECO:0000313|Proteomes:UP000009282}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 12485 / KCTC 12276 / FR1064
RC   {ECO:0000313|Proteomes:UP000009282};
RX   PubMed=22123761; DOI=10.1128/JB.06296-11;
RA   Bian F., Qin Q.L., Xie B.B., Shu Y.L., Zhang X.Y., Yu Y., Chen B.,
RA   Chen X.L., Zhou B.C., Zhang Y.Z.;
RT   "Complete genome sequence of seawater bacterium Glaciecola nitratireducens
RT   FR1064T.";
RL   J. Bacteriol. 193:7006-7007(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP003060; AEP28953.1; -; Genomic_DNA.
DR   RefSeq; WP_014107828.1; NC_016041.1.
DR   AlphaFoldDB; G4QJ85; -.
DR   STRING; 1085623.GNIT_0809; -.
DR   KEGG; gni:GNIT_0809; -.
DR   eggNOG; COG3706; Bacteria.
DR   HOGENOM; CLU_381249_0_0_6; -.
DR   OrthoDB; 8572793at2; -.
DR   Proteomes; UP000009282; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR   PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009282};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        25..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        60..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        95..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        124..142
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..215
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          591..726
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
SQ   SEQUENCE   726 AA;  81424 MW;  4BAAEBDAD06C6449 CRC64;
     MIRHLEKDFD IKKLLAHTPQ HTESVFSTAV LVYGLNFGGL GALTNYFLSI PFYGHFSLYF
     GQIFVLICLI TRGLNAGIIA SVISATALAV KMDDPFLFII LVSETFAVHI FLRKGKVLLV
     ADVFYWLFIG VPLTLLLLLL TSNSSTELLI ISGLTISING IFGASVAALI YSFIPFQSVY
     RKYRGKPPKF ATIIFSLCML TVTLPTIAIS LVFTWQTTAQ KEQDLSNMLS KQGEQIMYVG
     EAFVNNHISA VKTLSSILSE SSFSIPVQTV LDSTAKNYPS FTSMLVSGPD GEILYASPEK
     YAMMLGRTKK HTLHTRTYFN DAKRTLEPQL SEAIEGVGFG NDAILTVSAP IVLNDQFLGI
     SQGAIRLSSF SKFKQEHIDD NEFYQYVITD RNNRIIFASD GLSLPMLSQF SYQPSNNILL
     RKIPELKLQN NKYLYYQTVT EHGWKITVLN SPSAVTQVIS QNFYILAVGL LITLVVFSFI
     ASQLSKRITL PLERLANHFN DTTFPEDIAK EAEISDEMIK VTDKLINSRE IMLNFQQQLT
     EQVQDKTKQL KSLNQKLYHL AQKDGLTNLL NRSGFDDLAQ TTFRNCVRNY VPLSMVLIDI
     DDFKQINDTY GHPFGDKCIV SIAQTLSKFC KRNTDLLGRY GGEEFIVLLS GGHIEEHHEL
     TKQIHRAVQK TTVSNSEITV KMTISIGISS LSSNYGMTYE GLVKSADEQL YKSKRTGKNK
     ISIYVQ
//