ID G4R8F1_PELHB Unreviewed; 619 AA.
AC G4R8F1;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Formate hydrogenlyase transcriptional activator {ECO:0000313|EMBL:AEQ52395.1};
GN OrderedLocusNames=KKY_2386 {ECO:0000313|EMBL:AEQ52395.1};
OS Pelagibacterium halotolerans (strain DSM 22347 / JCM 15775 / CGMCC 1.7692 /
OS B2).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Devosiaceae; Pelagibacterium.
OX NCBI_TaxID=1082931 {ECO:0000313|EMBL:AEQ52395.1, ECO:0000313|Proteomes:UP000008850};
RN [1] {ECO:0000313|EMBL:AEQ52395.1, ECO:0000313|Proteomes:UP000008850}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22347 / JCM 15775 / CGMCC 1.7692 / B2
RC {ECO:0000313|Proteomes:UP000008850};
RX PubMed=22156395; DOI=10.1128/JB.06343-11;
RA Huo Y.Y., Cheng H., Han X.F., Jiang X.W., Sun C., Zhang X.Q., Zhu X.F.,
RA Liu Y.F., Li P.F., Ni P.X., Wu M.;
RT "Complete genome sequence of Pelagibacterium halotolerans B2T.";
RL J. Bacteriol. 194:197-198(2012).
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DR EMBL; CP003075; AEQ52395.1; -; Genomic_DNA.
DR RefSeq; WP_014131544.1; NC_016078.1.
DR AlphaFoldDB; G4R8F1; -.
DR STRING; 1082931.KKY_2386; -.
DR KEGG; phl:KKY_2386; -.
DR PATRIC; fig|1082931.4.peg.2355; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_8_5; -.
DR Proteomes; UP000008850; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071:SF117; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF13188; PAS_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils}; Lyase {ECO:0000313|EMBL:AEQ52395.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008850};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 144..201
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 222..274
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 306..535
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
FT COILED 265..292
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 619 AA; 69116 MW; 7A99C7EB7259FFF2 CRC64;
MTEVLEALIS AKSDPVLVVD PVRDVLVFAN PAARSFFGAR LDEAATGTMR TLYGACIAQL
HIATEAALEQ GCYYASDLQP DGSTAMDTVE HQLVAIKTAD GPLLMITIAD LEQRRRRSID
HEANNYHRQG LEEWRRAERF FREIERENQL ILAAAGEGIF GVNADGVTTF VNPAAQAMLG
WKADDLVGKN MHAMVHYKHP DGSHYHGSDC PIYGAFRNGT INTVEDECFW RKDGSPIRVE
YTSTPIEDDG ALVGAVIVFR DISQRKQNEA QLREAMAENA RLRERLEMEN AYLQEEILSQ
SNHYDIIGSS SLIRKILKQI DLVAPTDANV LITGESGTGK ELVARAIHQA SHRSERPLIR
VNCAAIPREL FESEFFGHVK GAFTGALRDR IGRFELANGG TIFLDEVGEI PLDLQSKLLR
VVQDRRFERL GEERTREVDI RVIAATNRDL QKEVAKGNFR EDLYFRLNVF PVECAPLRDR
RDDIPVLADH FLKIACSRLN IASPVLTRAN IVELKAYSWP GNARELQNLI ERAAILARNG
RMQFSLNAPP QAAISPPSPA PRQLGDEILT RNQILELERQ NIRRALDLAD GRVSGAKGAA
ELLGMRPTTL YSRIKALEL
//
