ID G4RPL7_THETK Unreviewed; 450 AA.
AC G4RPL7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Phosphomethylpyrimidine kinase fused to uncharacterized domain {ECO:0000313|EMBL:CCC81512.1};
DE EC=2.7.4.7 {ECO:0000313|EMBL:CCC81512.1};
GN Name=thiD {ECO:0000313|EMBL:CCC81512.1};
GN OrderedLocusNames=TTX_0857 {ECO:0000313|EMBL:CCC81512.1};
OS Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435
OS / Kra 1).
OC Archaea; Thermoproteota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC Thermoproteus.
OX NCBI_TaxID=768679 {ECO:0000313|EMBL:CCC81512.1, ECO:0000313|Proteomes:UP000002654};
RN [1] {ECO:0000313|EMBL:CCC81512.1, ECO:0000313|Proteomes:UP000002654}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1
RC {ECO:0000313|Proteomes:UP000002654};
RX PubMed=22003381; DOI=10.1371/journal.pone.0024222;
RA Siebers B., Zaparty M., Raddatz G., Tjaden B., Albers S.V., Bell S.D.,
RA Blombach F., Kletzin A., Kyrpides N., Lanz C., Plagens A., Rampp M.,
RA Rosinus A., von Jan M., Makarova K.S., Klenk H.P., Schuster S.C.,
RA Hensel R.;
RT "The complete genome sequence of Thermoproteus tenax: a physiologically
RT versatile member of the Crenarchaeota.";
RL PLoS ONE 6:E24222-E24222(2011).
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DR EMBL; FN869859; CCC81512.1; -; Genomic_DNA.
DR RefSeq; WP_014126768.1; NC_016070.1.
DR AlphaFoldDB; G4RPL7; -.
DR STRING; 768679.TTX_0857; -.
DR PaxDb; 768679-TTX_0857; -.
DR GeneID; 11261752; -.
DR KEGG; ttn:TTX_0857; -.
DR PATRIC; fig|768679.9.peg.866; -.
DR eggNOG; arCOG00020; Archaea.
DR HOGENOM; CLU_035788_0_0_2; -.
DR OrthoDB; 43786at2157; -.
DR Proteomes; UP000002654; Chromosome.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR019293; ThiN.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF10120; ThiP_synth; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:CCC81512.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002654};
KW Transferase {ECO:0000313|EMBL:CCC81512.1}.
FT DOMAIN 13..257
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 450 AA; 49192 MW; D1F24C526D56CDC8 CRC64;
MSWRVAMTIA GLDSGGGAGI HADIKTFAAL GVHGTTALTC VTAQNTYEVR AVQCMPREMV
RSQIMAVWDD MGIDAAKTGM LGTKEIIEEV ADVVSKLGFP LVVDPVMIAK SGAPLISEDA
MDALSRELLP IAKIVTPNRF EAERLTGMKI SSLEDAKRAA EKIHRELGSD IVIVKGGHLN
VQDAVDVVYI GGTFHELRTP RLNDRATHGT GCSFSAAIAA GLARGREPLE AIKTAKELIY
TAIKYGVPKG KGHWPVNPTA WVEIPAERWR VYEVMSQALS LLDRYAELFG PLIPEVQSNL
GYAIDPRYAE SREDVAAVPG RIVRYMNRAR PSGPPTFGAS DHVARKILAA VRHDPQKRAA
MNIRFDEGFI ERAKRAGYKV AIIDRRNEPK EVKEKEGGTM QWIVEESVRQ VGGVPDIIVD
LGDWGKEPMI TVLGKDPEDV IRTIIRIVSS
//
